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YEAR 3 SEMESTER I (2026/2027)

MIC3008: Chemical Pathology (Core: 4 credits)

Learning Outcomes
1. Determine the biochemical and molecular bases of main metabolic disorders.
2. Appraise analytical parameters associated with normal metabolism and
diagnostic use in disease.
3. Study the main analytical techniques in a chemical pathology context.

Course Synopsis
This course introduces the basic principles of chemical pathology. Emphasis is given
to automation and computerisation, selection of laboratory methods and equipment,
and method validation, all of which are central in the daily operation of a chemical
pathology laboratory.

The course also explores in-depth the biochemical and molecular aspects of major
metabolic diseases including nutrition, acid-base balance disorders, diseases of the
thyroid, pituitary, adrenal, ovarian, testicular and kidney hormones, the use of cancer,
bone and heart markers, and abnormalities in metabolism of proteins, lipids and
carbohydrates. Emphasis is given on the appropriate laboratory assessment for the
clinical diagnosis of these diseases.

Reference Texts
1. Rifai, N., Horvath, A.R. & Wittwer, C.T. (2018). Tietz Textbook of Clinical
Chemistry and Molecular Diagnostics (8 Edition). Elsevier.
th
2. Ahmed, N. (2017). Clinical Biochemistry (2 Edition). Oxford University Press.
nd
3. Al-Balushi, B. & Essa, M. (2019). A Quick Guide for Clinical Biochemistry. Nova
Science Pub. Inc.

Course Coordinator
Dr. Rozaida Poh Yuen Ying
rozaiday@um.edu.my
03-79676611

Course Assessment
Course will be assessed by Continuous Assessment (70%) and a Final Exam (30%)

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Biomedical Science Programme Guidebook 2024/2025