Page 209 - handbook 20152016

Faculty of Science Handbook, Session 2015/2016

Medium of Instruction: nucleotide and base excision repair, mismatch repair, and
English recombinational repair, sister chromatid exchange,
harlequin chromosomes, homologous recombination: the
Soft Skills Holliday model, the Meselson-Radding model, and the
CS4, CT2 double-stranded break model, gene conversion, site-
specific recombination, transposition: Ds and Ac,
Main References: transposons: insertion sequence, complex transposon,
1. SB Primrose and RM Twyman (2006) Principles of and composite transposon, transposon tagging, non-
Gene Manipulation and Genomics. Mendelian inheritance: maternal effect, epigenetic
2. Cockett, Noelle E.; Kole, Chittaranjan (2009). Genome inheritance (dosage compensation and genomic imprinting
Mapping and Genomics in Domestic - Prader-Willi syndrome and Angelman syndrome,
uniparental disomy: isodisomy and hetrerodisomy), and
extranuclear or cytoplasmic inheritance (maternal
SIL 3001 RESEARCH PROJECT IN GENETICS AND inheritance, pigmentation trait in plants, male-sterility trait,
MOLECULAR BIOLOGY petite traits: segregational petite mutants and vegetative
petite mutants - neutral petites and suppressive petites,
This course is intended to introduce practical aspects of chloroplast inheritance in Chlamydomonas, uniparental
the principles of Genetics and Molecular Biology. Students inheritance), evolution of the concept of the gene: function
will be exposed to research methodology in Genetics and and structure, the complementation test, the cis-trans test,
Moleculr Biology, critical scientific thinking, methods for homoalleles and heteroalleles, intragenic
problem solving, research ethics, record keeping, complementation, limitations on the use of the
presentation and scientific writing skills. complementation test.

Students are required to: Assessment Methods:
1) write a project proposal and carry out literature review Continuous Assessment: 40%
2) carry out experiments in the laboratory Final Examination: 60%
3) analyse data
4) write a dissertation Medium of Instruction:
5) present the results of the research English

Assessment Methods: Soft Skills
Continuous Assessment: 100% CT3, CS3, TS3, LL2
Consisting of;
Thesis: 80% Main References:
Proposal defence (oral) : 5% 1. Principles of Genetics 4th Edition (Snustad and
Progress defence (oral): 5% Simmons). Wiley Publications
Viva: 10% 2. Genetic Analysis and Principles (Brooker)
3. Other Basic Genetics text books
Medium of Instruction:
English
SIL 3005 FROM CELL TO SYSTEM
Soft Skills
CS3, CT3, LL2, EM2 This is an advanced course covering the following topics
of cellular and molecular biology of eukaryotes: revision of
the cell cycle and the molecular basis of cell cycle
SIL 3002 INDUSTRIAL TRAINING IN GENETICS AND regulation, apoptosis pathways, modes of cell signalling,
MOLECULAR BIOLOGY signalling molecules and their receptors, signal
transduction, signalling pathways, types of cell surface
The course provides students with an exposure to work at receptor, G protein coupled receptors, enzyme linked
a diagnostic or research laboratory outside of the receptors, non-receptor enzymes in signalling and second
university’s environment. Students are able to observe the messengers.
application of information from university courses and to
use it in the course of their attachment to these Assessment Methods:
laboratories. Continuous Assessment: 40%
Final Examination: 60%
Assessment Methods:
Continuous assessment: 100% Medium of Instruction:
Consisting of; English
Tests: 30%
Assignments: 30% Soft Skills
Presentations: 30% CS3, CT3, TS3, LL2
Participation in class and e-learning: 10%
Main References:
Medium of Instruction: 1. Krauss, et al. Biochemistry of signal transduction and
English regulation. Third Edition, Wiley.
2. Other text books will be referred to.
Soft Skills
CS3, CT2, TS2, LL2
SIL 3006 DEVELOPMENTAL GENETICS

SIL 3004 ADVANCED GENETICS This course focuses on concepts and understanding of
developmental biology with an emphasis on molecular
Gene mutation, the Luria-Delbrück fluctuation test, the ClB genetics. The topics cover are: overview of animal
chromosome, the Ames test for mutagenicity, trinucleotide development, early stages of embryonic development,
repeat expansion, DNA repair systems: direct repair, basic concept in developmental genetics, regulation and

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