Page 131 - handbook 20162017

Faculty of Science Handbook, Session 2016/2017

SIJ 1002 FUNDEMENTALS OF CHEMISTRY SIJ 2002 STRUCTURE AND FUNCTION OF
BIOMOLECULES
This course covers the basic principles of physical and This course consists of several experiments: isolation
organic chemistry with application to biological problems. methods, general biochemical analysis procedures,
This course is intended primarily for biochemistry majors. demonstration as well as theory regarding the latest
This course will discuss topics on the fundamental techniques and instrumentation used in the laboratory.
principles of physical chemistry which include chemical Basic diagnostic tests will also be conducted. This course
equilibrium, acidity and basicity, kinetics, thermodynamics will also emphasise quantitative data analysis.
and ligand-protein interaction. Basic principles of organic Assessment Methods:
chemistry, including fundamental aspects of organic and Continuous Assessment: 40%
biological structures and bonding, stereochemistry, the Practicals: 60%
effect of structure on physical and chemical properties will
be discussed. A detailed analysis of organic chemical Medium of Instruction:
reactivity, including reactive intermediates and English
mechanistic principles of the various groups of organic
compounds like alkanes and cycloalkanes, alkenes, Soft Skills:
CT3, LL2
alkynes, aromatics, alkyl halides, alcohols, ethers, thiols,
amines, carbonyls and derivatives will be covered. Main References:
th
1. Biochemistry, 7 ed (2012); Lubert M Stryer:
Assessment Methods: Macmillan Education.
Continuous Assessment: 40% 2. Textbook of biochemistry with clinical correlations,
Final Examination: 60% 6 ed; Ed by Thomas M Devlin; John Wiley & Sons
th
Inc (downloadable).
Medium of Instruction: 3. Biochemistry; 4 ed,(2011) Voet & Voet, Wiley
th
English 4. Biochemistry; 5 Ed, Garrett & Grisham:
th
Brooks/Cole Cengage Learning.
Soft Skills: 5. A journey from amino acids to proteins; Saad
CS3, CT3, LL1. Tayyab & Amru Nasrulhaq Boyce; Uni Malaya
Press.
Main References:
1. John E. McMurry. (2011). Organic Chemistry, 8 th
edition. Cengage Learning. Bab 1,3,4,6,7,8,9,10,11. SIJ 2003 ENERGETICS, METABOLISM AND
2. John McMurry. (2012) Organic Chemistry: a biological REGULATION OF CARBOHYDRATE
approach, 8 edition. New Jersey: Cengage Learning. AND LIPIDS
th
Bab 1,3,4,5,6,7,8,9,10,13,14,15,16,18.
3. Alan Cooper. (2012). Biophysical Chemistry, 2 nd The students will learn the principles of bioenergetics,
edition. RSC Pub, Cambridge. biosynthesis and catabolism of the primary
4. Predrag-Peter Ilich. (2014) Selected Problems in macromolecules, and regulatory mechanisms involved in
Physical Chemistry [e.book]: Strategies and intermediary metabolism.
Interpretations, Springer, Berlin Heidelberg.
5. Gordon G. Hommes (2008) Physical Chemistry for the The course encompasses the following topics: (1)
Biological Sciences, Wiley-Interscience. Concept of energy in metabolism and energy production
by aerobic and anaerobic respiration, and fermentation;
(2) Biosynthesis and catabolism of primary
macromolecules (carbohydrate, lipid, sulphur
SIJ 2001 PRINCIPLES OF BIOCHEMICAL ANALYSIS compounds); (3) Regulation and integration of metabolic
processes.
The course contains the quantitative aspects of
Biochemistry where the emphasis will be given to the Assessment Methods:
areas of acid-base, pH, buffer preparation, titration, Continuous Assessment: 40%
enzyme kinetics, bioenergetics and radioactivity. The Final Examination: 60%
course will also include current and “classical” analytical
methods – gels, TLC, qPCR, MS, HPLC, LC-MS Medium of Instruction:
English
Assessment Methods:
Continuous Assessment: 40% Soft Skills:
Final Examination: 60% CS3, CT3, LL2
Medium of Instruction: Main References:
English 1. Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto
th
Jr and Lubert Stryer (2015). Biochemistry (8 edition).
Soft Skills: New York: W.H. Freeman.
CS3, CT3, TS2, LL2. 2. Christopher K Mathews, Kensal E van Holde, Dean R
Appling (2012). Biochemistry (4 edition). Pearson
th
Main References: Education.
1. Principles of Biochemistry, 2013 (4th Edition or later). 3. Donald Voet, Judith G. Voet (2011).Biochemistry (4 th
Voet, Voet & Pratt edition) .New York: John Wiley.
2. Fundamentals of Biochemical Calculations, Second 4. Reginald H. Garrett and Charles M. Grisham (2013).
Edition (2007). Krish Moorthy Biochemistry (5th edition). Brooks/Cole, Cengage
Learning.

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