Page 127 - handbook 20162017

Faculty of Science Handbook, Session 2016/2017

Main References: SIK 3010 ANALYTICAL BIOCHEMISTRY
Selected research papers and other publications.
This course covers chromatography principles and
techniques, together with the use of spectrophotometer,
SIK 3008 ANALYSIS OF DRUGS radioimmunoassay and autoanalyser.
The course introduces the basic principle of drug Assessment Methods:
standardization and regulation to provide student sufficient Continuous Assessment: 40%
skill to be able to evaluate the analysis drug in laboratory. Final Examination: 60%
This course exposes the students to how a drug is
analysed and how drug preparation is manufactured and Medium of Instruction:
regulated. English
Assessment Methods: Soft Skills:
Continuous Assessment: 40% CS2, CT2, LL2
Final Examination: 60%
Main References:
rd
Medium of Instruction: 1. Holme, DJ. (1998). Analytical Biochemistry (3 Ed).
English Longman, UK
2. Voet, Donald (2004). Fundamentals of Biochemistry
nd
Soft Skills: (2 Ed). Wiley, New York.
CS1, CT2, LL2, EM2 3. Pratt, CW. (2004). Essential Biochemistry. John
Wiley, New Jersey
Main References:
1. Athanselis, SA., Smith, FP and Siegel, JA (2005).
Handbook of Forensic Derug Analysis. SIK 3011 CANCER BIOLOGY
2. Wagner, H. and Bladt, S. (1996). Plant Drug Analysis
(2 Ed). Springer Verlag Topics taught encompass nomenclature; staging;
nd
3. Basic Tests for Pharmaceutical Substances (1990), pathology; the carcinogenesis concept; classification and
WHO, Geneva type of carcinogen; epidemiology; etiology; therapy;
th
4. The Use of Essential Drugs, 9 Report of the WHO prevention and discussion on common cancers in
Expert Committee (2000). Technical Report Series Malaysia.
895
5. Flower, DR. (2002). Drug Design: Cutting Edge Assessment Methods:
Approaches. Royal Society of Chemistry, Cambridge. Continuous Assessment: 40%
Final Examination: 60%
SIK 3009 BASIC HERBAL MEDICINE Medium of Instruction:
English
The course consist of the introduction to the medicinal
plants and herbal medicine, history of medicinal plants, Soft Skills:
classification of medicinal plants, types and part of herbs CS2, CT2, LL2
use as a drugs, medicinal herbs system, drug herbs
application, drug herbs preparation, chemical constituents Main References:
of medicinal plants, herbal medicine formulation, 1. Cooper, G.M. (2009). The Cell: A Molecular Approach
th
development of herbal drugs, registration of herbal (5 ed.). ASM Press. Washington, D.C.
medicine. 2. Mendelsohn, J. et al. (2008). The Molecular Basis of
Cancer. Saunders/Elsevier. Philadelphia
Assessment Methods: 3. Weinberg, R.A. (2007). The Biology of Cancer.
Continuous Assessment: 40% Garland Science. New York.
Final Examination: 60% 4. King, R.J.B. & Robins, M.W. (2006). Cancer Biology
(3 ed.). Pearson/Prentice Hall, England.
rd
Medium of Instruction: 5. Macdonald, C.H.J. & Casson, F.A.G. (2004).
English Molecular Biology of Cancer (2 ed.). BIOS Scientific
nd
Publishers. London.
Soft Skills:
CS1, CT3, LL2
SIK 3012 STEM CELL BIOLOGY
Main References:
1. Edward. P. Claus; Varro. E. Tyler and Lynn. R. (1970) This lecture series is designed to give the student an in
Pharmacognosy 6th edition. depth understanding of stem cells, their uses in
2. Ethnopharmacology of Medicinal Plants: Asia and the regenerative therapies and how stem cells can be the
Pacific by christophe Wiert, Totowa, NJ :Humana initiating cells in diseases such as cancer. The course
Press Inc.,2007.; Via: Springer Ebook starts with general introduction to stem cell biology which
3. Muhamad Zakaria and Mustafa Ali Mohd (1994) covers definition, characterisation and signalling pathways
Traditional Malay Medicinal Plants, Penerbit Fajar involved in maintenance of stem cells. The use of stem
Bakti Sdn Bhd. cells in regenerative therapies will then be covered, along
4. Christophe wiart (2000) Mecidinal Plants of southeast with the generation of the alternative induced pluripotent
Asia, Pelanduk Publications. stem cells (iPSC) for use in patient specific therapies and
5. Malaysian Herbal Monograph (1999) Volume 1, for the study of disease. Finally the course will focus on
Published by the Malaysian Monograph committee. stem cells as the initiating cells of cancer and will consider
the adverse effects of possible genomic instabilities,
associated with long term culture of human stem cells.

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