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SIE1003 Biologi Sel / Cell Biology

Kredit / Credit : 2
Prasyarat Kursus / Course : -
Pre-requisite(s)
Bahasa Pengantar / Medium : Bahasa Inggeris / English Language
of Instruction

Sinopsis Kandungan Kursus / Synopsis of Course Content
This course is divided into three components namely Genetics, Cell Biology and Molecular Biology.
Content of each is stated below:

Cell Biology
This component will discuss the basic structures and functions of organelles and also processes
involving mitosis and meiosis.Students will also be introduced to prokaryotic and eukaryotic cells;
and the differences between these two types of cells.

Molecular Biology
In this component, students will first be refreshed on basic aspects of molecular genetics
(historical account, direct and indirect evidence of DNA as genetic materials, structure and
properties of DNA, DNA replication, transcription and translation in prokaryotes and how to
decipher genetic codes). The component will later discusses on regulation of gene expression in
prokaryotes (lac operon, catabolite repression and trp operon and attenuation), control by sigma
factor, anti-termination, post-transcriptional control of RNA (trans- and cis-acting regulators), and
finally the applications of these knowledge in DNA recombinant technology.

Genetics
This component comprises a quick introduction of Mendel’s Law, the concept of alleles, loci, genes
and chromosomes and test crosses. Students will be first refreshed on probability calculations,
the Punnet square and genetic linkage & mapping methods. The component will
later discuss deeper topics of inheritance which include Extensions to Mendelian Inheritance
Concept (Epistasis, Sex linkage), Sex influenced inheritance and Pedigree analyses. At the
end of this component students will be exposed to topics such as Human Genetics, Genetic
Counselling and finally a brief introduction to Population Genetics and Hardy-Weinberg Equilibrium.

Kaedah Pentaksiran / Assessment Methods
Pentaksiran Berterusan / Continuous : 50%
Assessment
Peperiksaan Akhir / Final Examination : 50%

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