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SIC3033 Produk Semulajadi dan Biosintesis / Natural Products and Biosynthesis

Kredit / Credit : 3

Prasyarat Kursus / Course : -
Pre-requisite(s)
Bahasa Pengantar / Medium : Bahasa Inggeris / English Language
of Instruction

Sinopsis Kandungan Kursus / Synopsis of Course Content

Classification of natural products. Biosynthesis of natural products, such as alkaloids, terpenoids,
flavonoids, lignans and glycosides. Separation strategies and spectroscopic methods for structural
elucidation of natural products. Biochemical constraints and investigation techniques: biosynthetic
reagents, enzymes, biochemical assays and application of isotopic labelling (esp. in conjunction with
13C NMR) in the study of biosynthetic processes.

Kaedah Pentaksiran / Assessment Methods
Pentaksiran Berterusan / Continuous : 40%
Assessment
Peperiksaan Akhir / Final Examination : 60%

SIC3028 Kimia Analisis Lanjutan / Advanced Analytical Chemistry

Kredit / Credit : 3
Prasyarat Kursus / Course : -
Pre-requisite(s)
Bahasa Pengantar / Medium : Bahasa Inggeris / English Language
of Instruction

Sinopsis Kandungan Kursus / Synopsis of Course Content

Trace Analysis. Introduction, techniques and limitations, and considerations in the implementation
of trace analysis

Sample preparation for inorganic and organic compounds. Steps in total analysis, dry, wet and
microwave sample digestion, selected solid phase extraction and liquid ph- se extraction techniques.

Spectrometry. Atomic absorption spectroscopy (AAS): atomization techniques such as flame
atomization, electrothermal (graphite furnace) atomization, hydride generation technique, glow
discharge, solidization, cold vapour technique. Atomic emission spectroscopy (AES): flame, arc-
spark and plasma AES (ICP-AES), atomic fluorescence spectroscopy (AFS): principle,
instrumentation, excitation sources, advantages, limitations. Separation Methods. Advanced aspects
on theory and process of separation in GC and HPLC, van Deemter equation, general resolution
equation and HETP, types and selection of stationary phases in GC, capillary GC, reversed phase
HPLC, effects of mobile phases in HPLC separations, instrumentation in GC and HPLC, detectors in
GC and HPLC, hyphenated techniques: GC-MS and LC-MS. Basic principles of capillary
electrophoresis.

Kaedah Pentaksiran / Assessment Methods
Pentaksiran Berterusan / Continuous : 50%
Assessment
Peperiksaan Akhir / Final Examination : 50%

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