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SIC2018 Kimia Organik II / Organic Chemistry II

Kredit / Credit : 2
Prasyarat Kursus / Course : Tiada / None
Pre-requisite(s)
Bahasa Pengantar / Medium : Bahasa Inggeris / English Language
of Instruction

Sinopsis Kandungan Kursus / Synopsis of Course Content

Nucleophilic addition, acyl substitution, and redox reactions; organometallic reagents in synthesis.
Enols and enolates: α-hydrogen acidity, keto-enol tautomerism; halogenation, alkylation,
regioselective enolate formation; aldol and enamine formation as enol equivalents. Conjugate
addition. Chemistry of amines: nitrogen chirality, reactions of amines.

Introduction to biomolecules: carbohydrates, amino acids, peptides and proteins, nucleic acids and
lipids.

Kaedah Pentaksiran / Assessment Methods
Pentaksiran Berterusan / Continuous : 40%
Assessment
Peperiksaan Akhir / Final Examination : 60%

SIC2024 Kaedah Spektroskopi dalam Kimia Organik / Spectroscopic Methods in Organic
Chemistry

Kredit / Credit : 2
Prasyarat Kursus / Course : -
Pre-requisite(s)
Bahasa Pengantar / Medium : Bahasa Inggeris / English Language
of Instruction

Sinopsis Kandungan Kursus / Synopsis of Course Content
IR spectroscopy: Characteristic functional group absorptions in organic molecules. UV spectroscopy:
electronic transitions and common chromophores in organic compounds; Beer-Lambert Law and
Woodward-Fieser Rules. Correlation between optical spectra and MO
theory.

NMR spectroscopy: 1H-NMR – Chemical shift: inductive and anisotropic effects; Spin-spin coupling:
geminal, vicinal, and allylic coupling, Karplus equation; examples of 1H-1H splitting
patterns; techniques to improve NMR spectra: use of shift reagents. 13C NMR: completely-coupled,
completely-decoupled, off-resonance-decoupled; APT and DEPT spectra; carbon chemical shifts
and functional groups.

Mass spectrometry: EIMS – molecular ions, isotope peaks, fragmentation ions and patterns.
HREIMS and determination of molecular formula of organic compounds. Application of combined
techniques in organic structure determination.

Kaedah Pentaksiran / Assessment Methods
Pentaksiran Berterusan / Continuous : 40%
Assessment
Peperiksaan Akhir / Final Examination : 60%

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