Page 119 - FINAL_HANDBOOK_20252026

Faculty of Science Handbook, Academic Session 2025/2026

Core Courses Molecular basis of mutations and DNA
repair; Spontaneous and inducible;
SIR1001 FUNDAMENTAL Introduction to DNA Recombinant
MICROBIOLOGY Technology.

Introduction to concepts and basic Assessment Methods:
techniques of microbiology, evolution, Continuous Assessment: 50%
structure and function of prokaryotic, Summative Assessment: 50%
dissemination, control and identification of
microorganisms. Exposure to aseptic
laboratory techniques for the transfer, SIR1003 BIOCHEMISTRY
isolation and stain of microorganisms.
This course encompasses structure and
Assessment Methods: physical characteristic of water, acid and
Continuous Assessment: 50% base, pH and pK; classification, structure
Summative Assessment: 50% and function of carbohydrates, lipids,
amino acids and proteins; nucleic acids and
molecular biology; characteristic of
SIR1002 FUNDAMENTAL GENETICS enzyme and the regulation of enxyme
activity; Biological Metabolism
This is a fundamental course covering the Fundamentals, catabolism and anabolism
following topics of Gametogenesis; of macromolecules in cell.
Mendelian Principles; Complete,
incomplete, and co-dominance; Multiple Assessment Methods:
alleles; Pedigree analysis; Chi-square test; Continuous Assessment: 50%
Probability and Statistics (Binomial Summative Assessment: 50%
expansion and factorial); Gene
Interactions; Epistatic ratios; Sex
determination; Sex linkage; Linkage map SIR1004 CONCEPTS OF GENETIC
(2-point cross; 3-point cross); From ENGINEERING
genotypes to phenotypes; Introduction of
Human Genetics; Counselling; Population This course emphasise on the isolation of
genetics and Hardy- Weinberg Equilibrium; DNA and RNA, vector for gene cloning;
Historical account of Molecular Genetics: various techniques on the transformation
Direct and indirect evidence of DNA as of eukaryotic and prokaryotic cells,
genetic materials; Chemical composition of identification of transformants, PCR
nucleic acids; Structure; properties of DNA; technique, Southern & Northern
DNA replication in prokaryotes, hybridisations, Sanger sequencing, NGS,
polymerase activity; Transcription: mutagenesis, genome editing techniques.
promoter function and specificity,
termination of transcription; Translation, Assessment Methods:
ribosome and tRNA specificity. Amino acid Continuous Assessment: 50%
charging. Deciphering the genetic code; Summative Assessment: 50%
Regulation of gene expression in
prokaryotes: lac operon; catabolite
repression; trp operon and attenuation;
Control by sigma factor, anti-termination;

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