Page 190 - FINAL_HANDBOOK_20252026

Part C: Chemical Thermodynamics Second law of sampling, confidence limits, measurement
thermodynamics. Thermodynamic properties of uncertainty, significant figures, test for mean,
multicomponent mixtures. Equilibrium of chemical rejection of analytical data.
reactions. Phase equilibrium: phase transition and
classification; phase rule, phase diagram for Complexometric titration. EDTA complexometric
multicomponent system (liquid-vapour, liquid-liquid titrations, back titration, metal indicators, masking
and liquid-solid) and applications. agent.

Part D: Macromolecules. Introduction to Spectrometry. Interaction of light energy between
macromolecules and polymers. Kinetics of free atoms and molecules; quantitative aspects of
radical polymerisation. Distribution and absorption. Molecular spectrometric techniques –
determination of molecular weights. Solubility and UV / Visible, IR, NIR; dispersion, absorption,
conformation of polymers. fluorescence and emission. Spectrophotometric
instruments; Atomic emission spectroscopy and
Assessment Weightage atomic absorption spectrometry: An introduction
Continuous assessment 40% uses of spectrophotometry.
Summative assessment 60%
Separation Methods. Introduction to the theory and
References: process of separation in GC and HPLC, ion
1. P. W. Atkins, Physical Chemistry, 11th ed., Oxford exchange chromatography, solvent extraction,
University Press, 2018. partition coefficient, multiple extraction, efficiency.
2. P. W. Atkins and R. S. Friedman, Molecular
Quantum Mechanics, Oxford University Press, Electroanalytical Chemistry.
2011, 5th Edition. Quantitative analysis – standard addition technique
3. J. P. Lowe and K. A. Peterson, Quantum and internal standard technique; Potentiometry –
Chemistry, Elsevier Academic Press, 2011, 3rd indicator and reference electrode, pH glass
Edition. electrode, ion selective electrodes.
4. R. J. Young and P. A. Lovell, Introduction to
Polymers, CRC Press, 2011, 3rd Edition. Assessment Weightage
Practical 30%
Continuous assessment 20%
SIC2021 PRACTICAL OF PHYSICAL Summative assessment 50%
CHEMISTRY II
References:
Thermodynamic properties of liquid-vapour phase 1. 1.D. A. Skoog, D. M. West, F.J. Holler & S.R
equilibrium, heat of neutralisation, determining Crouch, Fundamentals of Analytical Chemistry, 9th
activity coefficients via emf measurements, ionic ed., Cengage, Brooks/ Cole, 2014.
transport numbers, partial molar properties of 2. 2.D.C. Harris, Quantitative Chemical Analysis, 9th
solutions, kinetics of chemical reaction, ed., WH Freeman, 2015.
determination of mean activity coefficient and 3. 3.D.A. Skoog, F.J. Holler & S.R. Crouch (2017)
solubility of potassium hydrogen tartrate (KHT) in Principles of instrumental Analysis, 7th ed,
aqueous solution. Cengage Learning.

Assessment Weightage
Continuous assessment 100% SIC2023 MOLECULAR SPECTROSCOPY

References: Basic Spectroscopy. Vibrational, Rotational,
1. Laboratory Manual Physical Chemistry II, Electronic and Nuclear Magnetic Resonance
Department of Chemistry, Universiti Malaya. (NMR) Spectroscopy. Components in a
2. P. W. Atkins, J. De Paula And J. Keeler, Atkin’s spectrophotometer, experimental setup of Fourier
Physical Chemistry, Oxford University Press, 2018, Transform. Rotational, vibrational and rotational-
11th Edition. vibrational spectroscopy. Introduction of Raman
3. G.M. Barrow, Physical Chemistry, McGraw-Hill, 6th effect. Electronic spectroscopy of atoms and
Ed., 2011. molecules; electronic term symbols for atoms and
molecules. Introduction of photoelectron
spectroscopy. Basics of diatomic and polyatomic
SIC2022 ANALYTICAL CHEMISTRY I molecular electronic spectroscopy. Magnetic nuclei
in an external magnetic field. FT NMR
Introduction. Classical analysis, concentration experiments. Boltzman distribution and population
systems/units, sampling in analysis. of energy levels. Relaxation processes and width
of spectral lines. High resolution NMR spectra:
Data Treatment. Precision and accuracy, statistical chemical shift and spin-spin coupling. First-order
methods for error analysis, population and and second-order spectrum. Exchange processes.

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