Page 153 - Handbook Bachelor Degree of Science Academic Session 20202021

Faculty of Science Handbook, Session 2019/2020

Medium of instruction:
Assessment Methods: English
Practical: 25%
Continuous assessment: 15% References:
th
Final examination: 60% 1. T. W. G. Solomons, Organic Chemistry, 8 ed., Wiley,
2004.
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Medium of instruction: 2. J. McMurry, Organic Chemistry, 5 ed. Brooks/Cole.
English 3. R. M. Silverstein, F. X. Webster, Spectrometric
Identification of Organic Compounds, Wiley
References: 4. Kamaliah Mahmood, Noorsaadah Abd. Rahman, Kaedah
1. D. F. Shriver, P. W. Atkins, and C. H. Langford, Inorganic Kimia dalam Pengenalpastian Sebatian Organik,
nd
Chemistry, 2 ed., Oxford University Press, 1996. Penerbit Univ. Malaya.
2. F. A. Cotton & G. Wilkinson, Advanced Inorganic 5. P. Crews, J. Rodriguez, M Jaspars, Organic Structure
Chemistry, 5 ed., John Wiley, 1988. Analysis, Oxford University Press, New York, Oxford,
th
3. R. L. Carter, Molecular Symmetry and Group Theory, 1998.
John Wiley, 1998.
4. N. N. Greenwood & A. Earnshaw, Chemistry of the
Element, Pergamon Press, 1984. SIC2003 PHYSICAL CHEMISTRY II
rd
5. G. L. Meisller & D. A. Tarr, Inorganic Chemistry, 3 ed.,
Pearson Prentice Hall, 2004. Quantum Chemistry
The origin of quantum theory; Postulates and general
principles of quantum mechanics: wavefunction, operator,
SIC2002 ORGANIC CHEMISTRY II eigenfunction, eigenvalue, probability, average value and
Schrodinger equation; Dynamic and motion of simple
Preparation and reactions of alkyl halides: nucleophilic microscopic systems: translational motion, harmonic
aliphatic substitution: S N1, S N2; and elimination reactions: oscillator and vibrational motion, angular momentum and
E1, E2. rotational motion; Electronic structures of hydrogen like
atoms and many-electron atoms: hydrogen atom, atomic
Preparation and reactions of alcohols (hydroboration, orbital, Pauli principle, aufbau principle, Hund's rules,
oxymercuration-demercuration, etc.), phenols, aryl halides electron configuration, Slater determinant, angular
and nucleophilic aromatic substitution, ethers and momentum coupling, atomic terms, spin-orbit and other
epoxides, thiols and sulfides; interactions, symmetry, atomic spectra and selection rules.

Use of organometallic reagents (RLi, RMgX, R 2CuLi) in Chemical Kinetics
synthesis amines and nitrogen-containing compounds. Complex reactions. Collision between molecules, gas
transport phenomenom. Collsion theory of uni, bi and
Carbonyl chemistry: preparation and reactions of aldehyde trimolecular gas reactions. Introduction to reaction rate
and ketones, nucleophilic addition at carbonyl carbon; theory.

Carboxylic acids and nitriles, carboxylic acid derivatives Chemical Thermodynamics
and nucleophilic acyl substitution; difunctional compounds Second law of thermodynamics. Thermodynamic
– keto acids, hydroxy acids/esters, and lactones. properties of multi component mixtures. Equilibrium of
chemical reactions. Phase equilibrium: phase transition and
Acidity of the -hydrogen in carbonyl compounds; enol- classification; phase rule, phase diagram for multi
keto tautomerism; component system (liquid-vapour, liquid-liquid and liquid-
Reactions which proceed via enols and enolate ions: solid) and applications.
racemization, -halogenation of aldehydes and ketones,
base-catalysed halogenation (haloform reaction). Assessment Methods:
Practical: 25%
Enolate ion alkylation: use of lithium enolates in alkylation, Continuous assessment: 15%
regioselective enolate formation: kinetic and Final examination: 60%
thermodynamic enolates; lithium enolates in alkylation of
ketones, esters, acids; alkylation of -dicarbonyl Medium of instruction:
compounds for example acetic ester and malonic ester English
synthesis; alkylation of nitriles, nitroalkanes and 1,3-
dithianes; alkylation of enamines. References:
h
1. P. W. Atkins, Physical Chemistry, 11 ed., Oxford
Enolate ion addition/condensation reactions: aldols, University Press, 2018.
crossed aldol, intramolecular aldol, such as Mukaiyama 2. Donald A. McQuarrie, Quantum Chemistry, University
aldol, Claisen, crossed Claisen, intramolecular Claisen Science Book, 1983
nd
(Dieckmann), Knoevenagel, acylation of enamines, etc. 3. F. J. Bockhoff, Elements of Quantum Theory, 2 ed.,
Addison-Wesley Pub. Company, 1976.
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Conjugate addition of enolates, for example, Michael 4. G. M. Barrow, Physical Chemistry, 6 ed., McGraw-Hill,
addition, enamines in conjugate addition; Robinson 1996.
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annulation, Mannich reaction, etc. 5. R. A. Alberty & R. J. Silbey, Physical Chemistry, 4 ed.,
John Wiley, 2010.
Preparation and use of silyl enol ethers, aza-enolates, and
enamines, as enol equivalents.

Assessment Methods:
Practical: 25%
Continuous assessment: 15%
Final examination: 60%

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