Page 155 - Handbook Bachelor Degree of Science Academic Session 20202021

Faculty of Science Handbook, Session 2019/2020

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2. P. W. Atkins, J. D. Paula, Physical Chemistry, 11 ed., 4. D. Williams, I. Flemming, Spectroscopic methods in
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Oxford University Press, 2018. organic chemistry, 6 ed., McGraw-Hill, 2007.
3. P. J. Hore, Nuclear Magnetic Resonance, Oxford 5. D. L. Pavia, G. M. Lampman, G. S. Kritz, J. A. Vyvyan,
University Press, 1995. Introduction to spectroscopy, 4 ed., Cengage, 2009.
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4. M. Diem, Modern Vibrational Spectroscopy, John Wiley,
1993. SIC2008 BIOMOLECULES
5. R. J. Silbey, R. A. Alberty, M. G. Bawendi, Physical
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Chemistry, 4 ed., John Wiley & Sons, Inc, 2005. Carbohydrates: mono-, oligo-, polysaccharides – structure,
classification, nomenclature, reactions and analysis.

SIC2007 SPECTROSCOPIC METHODS IN ORGANIC Lipids and terpenes: fatty acids, acyl glycerols,
CHEMISTRY prostaglandins, terpenoids, steroids – structure, reactions,
and biological relevance.
IR Spectroscopy
Characteristic group absorptions in organic molecules. Proteins: amino acids, peptides, and proteins – structure,
synthesis and degradation analysis.
UV Spectroscopy
Electronic transitions and common chromophores in Nucleic Acids: DNA, RNA and protein biosynthesis.
organic compounds; Beer-Lambert Law and Woodward-
Fieser Rules. Assessment Methods:
Continuous assessment: 30%
NMR Spectroscopy Final examination: 70%
Brief theory and origin of the NMR experiment; CW- and
modern pulsed FT-NMR; H-NMR: the chemical shift: Medium of instruction:
1
inductive and anisotropic effects; Spin-spin coupling: English
geminal and vicinal coupling, Karplus equation; examples
1
1
of H- H splitting patterns; allylic and long-range coupling; References:
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techniques for improving the NMR spectrum: use of shift 1. P. Y. Bruice, Organic Chemistry, 5 ed., Pearson, 2007.
reagents; homonuclear-decoupling; effect of higher field 2. H. S. Stoker, General, Organic and Biological
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strengths, etc.; Chirality and NMR: chiral resolving agents; Chemistry. 5 ed., Brooks/Cole, 2010.
13 C-NMR: natural abundance of C and use of pulsed FT 3. T. K. Lindhorst, Essentials of Carbohydrate Chemistry
13
rd
13
techniques; the C NMR spectrum: completely-coupled, and Biochemistry, 3 ed., Wiley, 2006.
completely-decoupled; off-resonance-decoupled; APT and 4. F.D. Gunstone, J. L. Harwood, A. J. Dijkstra, The Lipid
DEPT spectra. Carbon chemical shifts and functional Handbook, 3 ed., CRC Press, 2007.
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groups. 5. Zanariah Abdullah, Noorsaadah Abd. Rahman dan
Kamaliah Mahmood, Biomolekul Suatu Pengenalan.,
2D-NMR: COSY, HETCOR/HMQC/HSQC, and HMBC for Penerbit Universiti Malaya, 2001.
establishing molecular connectivity; 1-D NOE and 2-D
NOESY for determination of stereochemistry.
SIC2009 INTRODUCTION TO ENVIRONMENTAL
CHEMISTRY
Mass Spectrometry
EIMS – molecular ions, isotope peaks, and fragment ions; Natural Environment – the earth’s surface, atmosphere,
HREIMS and determination of molecular formula (dual- hydrosphere and elemental cycles.
sector, double-focussing instruments); principal
fragmentation patterns in major classes of organic Human impacts on natural environment – water pollution
compounds, McLafferty rearrangement and retro-Diels- and air pollution and treatment of pollutants.
Alder processes; Modern MS methods, ionization
techniques: e.g., CI-, APCI-, FD-, FAB-, DART, ESI-, and Assessment Methods:
MALDI-MS; analyzers: Quadrupole, Ion Trap, TOF; Continuous assessment: 30%
Hyphenated techniques: GC- and LC-MS: Common Final examination: 70%
instrument configurations: e.g., GC-EIMS, GC-TOF-, LC-
ESI-TOF-, LC-ESI-Q-TOF-, LC-MALDITOF-, and LC- Medium of instruction:
MALDITOF-TOF-MS. English

Application of combined techniques in organic structure References:
determination. 1. C. Bard, M. Cann, Environmental Chemistry, 5th edition,
W.H. Freeman and Company, New York, 2012.
Assessment Methods: 2. S.E. Manahan, Environmental Chemistry, 10th edition,
Continuous assessment: 30% CRC Press, Boca Raton, 2017.
Final examination: 70% 3. G. W. Vanloon, S. J. Duffy, Environmental Chemistry: A
global perspective, 4th edition, Oxford University Press,
Medium of instruction: London, 2017.
English 4. J.H. Seinfeld, S. N. Pandis, Atmospheric chemistry and
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physics: From air pollution to climate change, 3 edition,
References: Wiley, 2016.
1. R. M. Silverstein, F. X. Webster, D. J. Kiemle, 5. M. R. Harrison, Introductory Chemistry for the
Spectroscopic identification of organic compounds, 7 th Environmental Sciences, Cambridge University Press,
ed., John Wiley, 2005. May 2018.
2. Kamaliah Mahmood dan Noorsaadah Abd Rahman,
Kaedah Kimia dalam pengenalpastian Sebatian Organik,
Penerbit University of Malaya, 1998.
3. P. Crews, J. Rodriguez, M. Jaspars, Organic structure
analysis, 2 ed., Oxford University Press, New York,
nd
2009.
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