Page 159 - Handbook Bachelor Degree of Science Academic Session 20202021

Faculty of Science Handbook, Session 2019/2020

Assessment Methods: natural rubber; biosynthetic pathways, reaction types, and
Practical: 30% mechanistic aspects (esp. enolate-carbonyl reactions and
Continuous assessment: 20% biochemical cascades).
Final examination: 50%
Assessment Methods:
Medium of instruction: Continuous assessment: 30%
English Final examination: 70%

References: Medium of instruction:
th
1. C. D. Harris, Exploring Chemical Analysis, 4 ed., W.H. English
Freeman Publ, 2008.
th
2. G. D. Christian, Analytical Chemistry, 7 ed., John Wiley References:
& Sons, 2014. 1. H. S. Stoker, General, Organic and Biological Chemistry,
3. D. A. Skoog, F. J. Holler & S. R. Crouch, Principles of 5 ed., Brooks/Cole, 2010.
th
rd
Instrumental Analysis, 6 ed., Thomson Brooks/Cole, 2. D. Voet, and J. G. Voet, Biochemistry. 3 ed., Wiley,
th
2007. 2004.
4. D. Harvey, Modern Analytical Chemistry, McGraw Hill 3. Bu’Lock and B. G. Kurt Kimia Hasil Semulajadi, DBP,
Publ, 2000. Kuala Lumpur.
nd
5. D. A. Skoog, D. M. West, F. J. Holler & S. R. Crouch, 4. J. Mann, Secondary Metabolism, 2 ed., Oxford
Fundamentals of Analytical Chemistry, 9 ed., University Press, 1987.
th
Brooks/Cole Publ, 2014. 5. J. Mann, Chemical Aspects of Biosynthesis, Oxford
University Press, 1994.

SIC3007 ELECTROSYNTHESIS SIC3009 NATURALPRODUCTS CHEMISTRY

Electrosynthesis in industry focus on the synthesis of The influence of biosynthetic hypotheses and insights on
organic and inorganic chemicals; aluminium extraction, the syntheses of steroids. Investigation of selected natural
chloro-alkali process and sodium hydroxide. Laboratory products such as alkaloids, terpenoids, flavonoids, lignans,
techniques related to electrochemistry; glycosides. Semiochemistry. Separation methods for
electropolymerisation, electrochemical impedance natural product isolation. Spectroscopic methods for
spectroscopy, electrocatalysis, electroanalytical and structural elucidation of natural products.
instrumentation, quantities and qualitative data analysis
from various techniques. The analysis method enables the Assessment Methods:
determination of redox potential in any compound. Cyclic Continuous assessment: 30%
voltammetry method in diagnosis mechanism will be Final examination: 70%
introduced such as E, EC, CE or ECE reactions
mechanism. Medium of instruction:
English
Assessment Methods:
Continuous assessment: 30% References:
Final examination: 70% 1. J. Mann, Secondary Metabolism, Clarendon Press:
Oxford, 1995.
Medium of instruction: 2. P. M. Dewick, Medicinal Natural Products - A Biosynthetic
English Approach, John Wiley & Sons, 2009.
3. E.Fattorusso, O. Taglialatela-Scafati, Eds Modern
References: Alkaloids - Structure, Isolation, Synthesis and Biology;
1. C. M. A. Brett and A. M. O. Brett, Electrochemistry Wiley-VCH, 2008.
Principles, Methods and Applications, Oxford Uni. Press 4. J. H. Simpson, Organic Structure Determination Using 2-
Inc., 1993. D NMR Spectroscopy - A Problem-Based Approach,
2. P. T. Kissinger and W. R. Heinemmen, Laboratory Academic Press, 2008.
Techniques in Electroanalytical Chemistry, Marcel 5. S. Stefan Berger, D. Sicker, Classics in Spectroscopy,
Dekker Inc., 1984. Wiley-VCH, 2009.
3. D. Pletcher and F.C. Walsh, Industrial Electrochemistry,
Blackie Academic and Professional, 1993. SIC3010 ORGANIC SYNTHESIS
4. D. B. Hibbert, Introduction to Electrochemistry, MacMillan
Press Ltd., 1993. Retrosynthetic analysis and synthesis design. Selectivity in
5. K. B. Oldham, J. C. Myland, A. M. Bond, Electrochemical synthesis: chemo-, regio-, and stereoselectivity. Synthesis
Science and Technology: Fundamentals and of acyclic and cyclic compounds. Concept of umpolung;
Applications, John Wiley & Sons, Ltd, 2011. functional group interconversion. Use of organometallic
6. J. Wang, Analytical Electrochemistry, John Wiley & Sons, reagents in syntheses. Asymmetric synthesis; selected
Inc., 2006. examples from classical and contemporary syntheses.
7. A. J. Bard and L. R. Faulkner, Fundamentals and
Applications, John Wiley & Sons. Inc., 2001. Assessment Methods:
Continuous assessment: 30%
Final examination: 70%
SIC3008 BIOSYNTHESIS
Medium of instruction:
Biochemical constraints and investigation techniques: English
biosynthetic reagents, enzymes, biochemical assays and
application of isotopic labelling (esp. in conjunction with
13C NMR) in the study of biosynthetic processes.

Biosynthesis of selected natural products: polyketides, fatty
acids, prostanoids, aromatic compounds (e.g. Shikimic
acid), macrocyclic antibiotics, terpenes, terpenoids, and

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