Page 160 - Handbook Bachelor Degree of Science Academic Session 20202021

Faculty of Science Handbook, Session 2019/2020

References:
1. Warren, S., Organic Synthesis: The Disconnection Assessment Methods:
Approach, John Wiley and Sons, Chichester, New York, Continuous assessment: 30%
Brisbane, Toronto, Singapore, 1982. Final examination: 70%
2. F. A. Carey and R. J. Sundberg, Advanced Organic
Chemistry, Part B: Reactions and Synthesis, 4 ed., Medium of instruction:
th
Plenum Press, New York & London, 2002. English
nd
3. M. B. Smith, Organic Synthesis, 2 ed., McGraw Hill Inc,
2001. References:
4. M. B. Smith and J. March, March's Advanced Organic 1. M. Niyaz Khan, Micellar catalysis, CRC Press, Taylor &
Chemistry: Reactions, Mechanisms, and Structure Francis Group, 2006.
th
(March's Advanced Organic Chemistry), 5 ed., Wiley- 2. W. P. Jencks, Catalysis in Chemistry and Enzymology,
Interscience; 2001. McGraw-Hill, New York, 1969.
5. W. A. Smit, A. F. Bochkov and R. Caple, Organic 3. J. March, Advanced Organic Chemistry: Reactions,
th
Synthesis: The Science Behind the Art, RSC, 1998. Mechanisms and Structure, 4 ed., McGraw-Hill, 1992
4. J. Hine, Structural Effects on Equilibria in Organic
Chemistry, Wiley, 1975.
SIC3011 MECHANISTIC ORGANIC CHEMISTRY 5. C. Reichardt, Solvents and Solvent Effects in Organic
Chemistry, VCH, New York, 1988.
Reactive intermediates in organic chemistry including
carbocations, free radicals, carbenes, nitrenes, and radical- SIC3013 ADVANCED MOLECULAR SPECTROSCOPY
ions. Chemistry of free radicals: reactions and mechanisms
of free radicals including abstraction, addition, Selections of topics are as follows:
rearrangement, cyclization and fragmentation; applications
of radical reactions in organic synthesis; reactions of Basic quantum mechanics and group theory for
carbenes, carbenoids, nitrenes, and ion-radicals, and spectroscopy; vibrational spectroscopy of polyatomic
applications in synthesis. Formation, stability, and molecules, selection rules and analysis of normal modes of
rearrangements of carbocations; tandem and cascade vibration, Raman spectroscopy, advanced electronic
cyclizations. Mechanistic details of selected classes of spectroscopy, and modern techniques in spectroscopy.
organic reactions such as nucleophilic substitution, Laser techniques and applications of lasers in
hydrolysis, polar rearrangements, electron-transfer spectroscopy.
reactions, photochemical reactions. Pericyclic reactions: Energy of a free electron in a magnetic field. EPR
molecular orbitals; conservation of orbital symmetry in spectrometer & first-derivative spectrum. The g-factor and
concerted reactions; theory (frontier orbital method, use of hyperfine structures: simple and complex hyperfine
correlation diagrams, aromatic transition state approach) patterns. Interpretation of isotropic hyperfine coupling
and applications of electrocyclic reactions, sigmatropic constants: spin Hamiltonian and perturbation theory. First-
rearrangements, and cycloadditions, including tandem and order and second-order hyperfine.
cascade processes, in organic synthesis.
Assessment Methods:
Assessment Methods: Continuous assessment: 30%
Continuous assessment: 30% Final examination: 70%
Final examination: 70%
Medium of instruction:
Medium of instruction: English
English
References:
References: 1. N. M. Atherton, Electron Spin Resonance, John Wiley &
1. R. B. Woodward and R. Hoffmann, The Conservation of Son Inc., 1973.
Orbital Symmetry, Academic Press Inc, 1970. 2. A. Carrington and A. D. McLachlan, Introduction to
2. J. Clayden, N. Greeves, S. Warren, P. Wothers, Organic Magnetic Resonance, Harper & Row and John
Chemistry, Oxford. Weatherhill Inc.,1969.
th
3. J. March, and M. Smith, Advanced Organic Chemistry, 3. P. Atkins, J. d. Paula, Physical Chemistry, 11 ed.,
th
6 ed., New York: John Wiley & Sons, 2007. Oxford University Press, 2018.
th
4. T. H. Lowry and K. S. Richardson, Mechanism and 4. J. M. Hollas, Modern Spectroscopy, 4 ed., John Wiley &
Theory in Organic Chemistry, 3 ed., Harper and Row, Sons, 2004
rd
st
1987. 5. I. N., Levine Molecular Spectroscopy, 1 ed., John Wiley
5. A. J. Bellamy, An Introduction to the Conservation of & Sons, 1975.
Orbital Symmetry, Longman, 1974. 6. J. L. Mchale, Molecular Spectroscopy, Crc Press, 2017.
6. I. Fleming, Frontier Orbitals and Organic Chemical 7. R. C. Maurya, & Amp; J. M. Mir, Molecular Symmetry And
Reactions, Wiley, 1976. Group Theory, De Gruyter 2019.5.
7. S. Sankararaman, Pericyclic Reactions - A Textbook: 8. H. Abramczyk, Introduction To Laser Spectroscopy,
st
Reactions, Applications and Theory, Wiley-VCH, 2005 Elsevier 1 Edition 2005.

SIC3012 PHYSICAL ORGANIC CHEMISTRY SIC3014 POLYMER CHEMISTRY II

Application of physical organic concepts in the Part A: Polymer Characterizations
determination of organic reaction mechanisms: kinetics and Characterization of a polymer system. Non-instrumental
energetics; stereochemistry; solvent effects; non-kinetic techniques – (a) density measurements /comparisons, and
and kinetic isotope effects; linear free energy relationships; (b) heating and burning tests. Instrumental techniques - (a)
sonochemistry; organic surface reactions. thermal analysis (DSC & TGA), (b) Spectroscopic
techniques (FTIR & NMR). Aspects of the strengths and
Catalysis: catalysis in molecules, approximation, induced weaknesses of these techniques in polymer
catalysis, covalent catalysis, nucleophilic catalysis, general characterization and their applications in research and
acid- and general-base catalysis, micellar catalysis and industry will be introduced. Relevant examples will be
enzymatic catalysis. discussed and set as assignments.
159