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Faculty of Science Handbook, Session 2017/2018

interactions, marker assisted breeding and plant genomics.
Related practicals will be given.
SIL 3005 FROM CELL TO SYSTEM
Assessment Methods:
This is an advanced course covering the following topics of Continuous Assessment: 40%
cellular and molecular biology of eukaryotes: revision of the Final Examination: 60%
cell cycle and the molecular basis of cell cycle regulation,
apoptosis pathways, modes of cell signalling, signalling Medium of Instruction:
molecules and their receptors, signal transduction, English
signalling pathways, types of cell surface
receptor, G protein coupled receptors, enzyme linked Soft Skills
receptors, non-receptor enzymes in signalling and second CS3, CT3
messengers.
Main References:
Assessment Methods: 1. Buchanan, Grusseim and Jones (2006) Biochemistry
Continuous Assessment: 40% and MolecularBiology of Plants, Pbls. John Wiley and
Final Examination: 60% sons (UK) ISBN 09430088399.
2. Genes IX, Benjamin Lewin (2007)
Medium of Instruction: 3. Information in Spectrum
English

Soft Skills SIL 3008 HUMAN GENETICS
CS3, CT3, TS3, LL2
This course starts by looking at the content and
Main References: organisation of the human genome. It involves describing
1. Krauss, et al. Biochemistry of signal transduction and the gene-related sequences (genes, introns, exons,
regulation. Third Edition, Wiley. regulatory regions, pseudogenes etc) and non-gene-
2. Other text books will be referred to. related sequences (unique to highly repetitive classes). The
student is then introduced to the Human Genome Project
and the processes involved. It includes physical and
SIL 3006 DEVELOPMENTAL GENETICS genetic mapping. The second part will focus on the
methods of medical genetic research, with old and new
This course focuses on concepts and understanding of techniques. This includes functional cloning, positional
developmental biology with an emphasis on molecular cloning and candidate gene approaches (functional
genetics. The topics covered are: overview of animal candidacy, positional candidacy, mutation screening
development, early stages of embryonic development, methods). At the end of the course, students will be
basic concept in developmental genetics, regulation and familiarised with current issues and research technology
differential gene expression, molecular genetics of which includes SNP analysis, microarray and proteomics.
pattern formation in Drosophila, development fate of each
cell in C. elegens, sex determination in yeast, Drosophila Assessment Methods:
and mammals, genetic specification of floral organ identity Continuous Assessment: 40%
Arabidopsis, stem cell, and ethical issues. Final Examination: 60%
Assessment Methods: Medium of Instruction:
Continuous Assessment: 40% English
Final Examination: 60%
Soft Skills
Medium of Instruction: CS3, CT3, TS3, LL2
English
Main References:
Soft Skills 1. Human Molecular Genetics (Strachan & Read)
CS3, CT2, TS3, LL2 2. Introduction to Human Genetics (Gustavo Maroni)

Main References:
1. Developmental biology (10th edition). Scott F. Gilbert. SIL 3009 EPIGENETICS AND GENE REGULATION
2013. Sinauer Associates, Inc.
2. Principles of Development (4th edition). Lewis Wolpert This course will provide a basic understanding of the role
and Cheryll Tickle. 2010. Oxford University Press. of epigenetics in gene regulation. Topics will include
3. Molecular Biology of the Cell (5th edition). Alberts B, chromatin remodelling, histone modifications, DNA
Johnson A, Lewis J, et. al. 2007. Garland Science. methylation, the importance of epigenetics in normal
cellular functions, evidence for epigenetics involvement in
disease.
SIL 3007 MOLECULAR BIOLOGY OF PLANTS
Assessment Methods:
Introduction to basic principles and current advancements Continuous Assessment: 40%
in plant molecular biology. This course covers theoretical Final Examination: 60%
and practical aspects that form the bases of current
approaches in plant improvement and biotechnology, Medium of Instruction:
including genetic engineering. Lectures include: structure, English
organisation and regulation of plant genes and cell
signalling in plant cells; molecular biology of plastids and Soft Skills
chloroplasts; organisation of mitochondrial DNA; molecular CS4, CT2, TS3, LL3
biology of nitrogen metabolism; molecular biology of
development; cell signalling, molecular plant-pathogen

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