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Faculty of Science Handbook, Session 2017/2018

Main References: current review will be given from up-to-date journal papers.
1. Epigenetics, C. David Allis, Thomas Jenuwein, and This course is most relevant to a genetics student, as
Danny Reinberg (2007) Cold Spring Harbor Laboratory various evidence points to cancer as having a genetic risk
Press factor that can transform cells from a benign to a cancerous
2. Epigenetics, Lyle Armstrong (2014) Garland Science state.
group
3. Cancer Epigenetics, Edited by Trygve Tollefsbol Assessment Methods:
(2009).CRC press, Taylor & Francis group Continuous Assessment: 40%
Final Examination: 60%
SIL 3010 GENOME ANALYSIS
Medium of Instruction:
This course looks into the various approaches and English
technologies that can be employed in answering research Soft Skills
questions and contribute towards the development of field CS3, CT2, TS3, LL2
of genetics. The course will also discuss the strength and
weaknesses of each of these technologies, and underlines
the limitations on using these technologies. Main References:
1. Immunology 5th edition Richard A. Goldsby, Thomas
J. Kindt, Barbara A. Osborne and Janis Kuby
Assessment Methods: 2. Cellular and Molecular Immunology 7th edition Abul K.
Continuous Assessment: 100%
Abbas, Andrew H. Lichtman & Shiv Pillai
Medium of Instruction: 3. Immunobiology: The Immune System in Health and
Disease 4th edition Charles A. Janeway, Paul Travers,
English Mark Walport and J Donald Capra
4. The Biology of Cancer. Robert A.Weinberg (2006).
Soft Skills Garland Science Textbooks
CS4, CT3, LL2, ET2
5. Journals
Main References:
1. Genome Analysis and Bioinformatics: A Practical SIL 3013 GENETICS AND BIOTECHNOLOGY OF
Approach (2009), Sharma, T. R. VIRUSES
2. Bioinformatics: Sequence and Genome Analysis
(2006), David Mount.
3. Analysis of Genes and Genomes (2004), Richard J. This course will involve theoretical and practical skills
related to the genetics and the biotechnological application
Reece. of viruses. Topics will include the biology and genetics of
plant, animal and medically important viruses and their
SIL 3011 APPLICATIONS OF RECOMBINANT DNA importance in human lives and activities. Virus life cycles
TECHNOLOGY and diversity will be compared and discussed
together with the mechanisms of transmission and control,
especially related to medicine and agriculture. The use of
This is an advanced course covering applications of viruses and viral genes in biotechnology ranging from
recombinant DNA technology to medicine, agriculture,
industry and research. Health care: diagnostics for research and therapeutic use to applications in agriculture
and industry will also be discussed.
infectious and genetic disease, gene therapy, vaccine
development, RNAi. Agriculture: Transgenic plant Assessment Methods:
technology, transgenic mitigation. Forensic: genetic means
of identification. Industrial and Pharmceutical: various Continuous Assessment: 40%
eukaryotic production systems (yeast, insect, plant, Final Examination: 60%
mammalian), prokaryotic production (E.coli). Research: Medium of Instruction:
gene discovery and isolation, mutagenesis, proof of gene English
function, development of new technologies (across many
fields).
Soft Skills
Assessment Methods: CS1, CT2, TS3, LL3
Continuous Assessment: 40% Main References:
Final Examination: 60%
1. Structure and Physics of Viruses: An Integrated
Medium of Instruction: Textbook Series: Subcellular Biochemistry, Vol. 68
Mateu, Mauricio G. (Ed.) 2013, Springer. ISBN 978-
English 94-007-6552-8 2.
2. Understanding Viruses (Second Edition)Teri Shors
Soft Skills (Ed), 2013. Jones and Bartlett. ISBN-13:
CS3, CT3, TS3, LL2
9781449648923
Main References: 3. Review papers and journal articles will be supplied via
course webpage
1. Molecular Biotechnology, principles and applications
of recombinant DNA 4th edition. Glick BR & JJ
Pasternak 2009 (ASM Press) SIL 3014 ADVANCED IMMUNOGENETICS
2. Other recommended materials during lectures
The course gives an understanding of the importance of the
failure and deficiency of the immune system in providing
SIL 3012 CANCER AND TUMORIGENESIS
protection. The introduction will focus on various major
The course gives an understanding on cancer and why it is components of the immune system and in situations when
it fails in its function as a result in deficiency of its various
seen as a much feared disease worldwide. The initial components, and the different resulting manifestation in the
development and treatment of cancer will be discussed. A host. These resulting immune failure diseases will be

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