Page 125 - FINAL_HANDBOOK_20252026

Faculty of Science Handbook, Academic Session 2025/2026

Characteristics of Pathogenicity Islands, Assessment Methods:
endotoxin, exotoxin- characteristics of Continuous Assessment: 50%
exotoxins, toxin types, secretion and Summative Assessment: 50%
excretion systems, roles of toxins in
diseases; Mechanism of antimicrobial
resistance and how bacteria become SIR3027 EPIGENETICS AND GENE
resistant to antibiotics. Examples of REGULATION
specific bacterial pathogens.
Practical component on laboratory skills. This course will provide a basic
understanding of the role of epigenetics in
Assessment Methods: gene regulation. Topics will include
Continuous Assessment: 60% chromatin remodelling, histone
Summative Assessment: 40% modifications, DNA methylation, the
importance of epigenetics in normal
cellular functions, evidence for epigenetics
SIR3025 CYTOGENETICS involvement in disease.

This course focuses on structure and Assessment Methods:
function of chromosomes, movement of Continuous Assessment: 50%
chromosomes during mitosis, Summative Assessment: 50%
modifications of mitosis, movement of
chromosomes during meiosis, correlation
between meiosis and Mendelian laws, SIR3028 EUKARYOTIC CELL
aberrant meiosis, methods in cytogenetics, SIGNALLING
karyotype analysis and nomenclature,
variation in chromosome types, variation This is an advanced course covering the
in chromosome number and structure. following topics of cellular and molecular
biology of eukaryotes: in the mammalian
Assessment Methods: system, topics covered are revision of the
Continuous Assessment: 40% cell cycle and the molecular basis of cell
Summative Assessment: 60% cycle regulation, apoptosis pathways,
modes of cell signalling, signalling
molecules and their receptors including G
SIR3026 DEVELOPMENTAL protein coupled receptors, enzyme linked
GENETICS receptors, non- receptor enzymes in
signalling and second messengers. In plant
This course focuses on basic concepts and system, topics covered are signal
general principles in embryonic perception, transduction and integration
development, genetic approach to in plants; intracellular signal transduction,
development, genetic toolkit for amplification and integration via second
Drosophila development, spatial messenger and MAPK cascades; signal
regulation of gene expression in transduction from phytochromes; seedling
development, post-transcriptional development; stomatal aperture; cell
regulation of gene expression in senescence and apoptosis; and cell
development, the many roles of individual senescence metabolism.
toolkit genes, development and disease.

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