Page 73 - Handbook Bachelor Degree of Science Academic Session 20202021

Faculty of Science Handbook, Academic Session 2020/2021

SIJ 3012 APPLIED BIOCHEMISTRY AND 3. Bioactive Natural Products – Detection, Isolation and
BIOTECHNOLOGY Structural Determination (2007), Steven M. Colegate,
Russell J. Molyneux; CRC Press
nd
The course stars with the introduction to applied 4. Natural Products from Plants (2006) 2 ed. Leland J
biochemistry, biotechnology and the use of several Cseke, Ara Kirakosyan, Peter B Kaufman, Sara L
techniques in current research in biotechnology. The Warber, James A Duke, Harry L Brielmann; Taylor &
course would also look into the production of several Francis
secondary metabolites and their application. It will also look 5. Natural Product Chemistry for Drug Discovery (2009),
into the roles of biochemistry in different aspect of area Anthony D Buss, Mark S Butler; RSC Publishing
either it be in agricultural, environmental or medicinal.

SIJ 3014 MOLECULAR STRUCTURAL BIOLOGY
Assessment Methods:
Continuous Assessment: 40% The course will introduce to students the structure of
Final Examination: 60% proteins at all levels, and how this relates to function. A non-
mathematical introduction of the basic principle of X-ray
Medium of Instruction: crystallography and other techniques used in structural
English studies. Nuclear magnetic resonance (NMR) is the second
most important technique for determining the three-
Main References: dimensional structure of macromolecules. Electron
1. Rosenberg E., DeLong E.F., Lory S., Stackebrandt Microscopy (EM) is a technique that is complementary to X-
E., Thompson F. (eds) (2013) ray crystallography as it enables the study of non-
The Prokaryotes: Prokaryotic Physiology and crystalline, very large or transient macromolecular
Biochemistry, 4th ed. Springer e-Books. structures. This course also introduces some
2. Yukawa H., Inui M. (eds) (2013) Corynebacterium methodologies for protein purification for structural studies.
glutamicum: Biology and Biotechnology. Springer e- It also examines the importance of protein-protein
Books. interactions and some techniques used for the study.
3. Lee, Y. K. Microbial Biotechnology: Principles and
Application (3rd ed.). Singapore: World Scientific Assessment Methods:
Publishing Company. Continuous Assessment: 40%
4. Advances in Biochemical Engineering/ Final Examination: 60%
Biotechnology, 135 (2013). Yellow Biotechnology I.
Insect Biotechnologie in Drug Discovery and Medium of Instruction:
Preclinical Research. Eds. Andreas Vilcinskas. English
Springer-Verlag Berlin Heidelberg. ISBN 978-3-642-
39862 Main References:
5. Basic of Biosciences Agriculture from Nagoya 1. Physical Biochemistry: Principles and Applications.
University –OpenCourseWare (http://ocw.nagoya- 2000. David Sheehan. Wiley .
u.jp/index.php?lang=en&mode=c&id=1) 2. Introduction to Protein Structure. Carl Branden and
OpenCourseWare (http://ocw.nagoya- John Tooze.Garland Publishing Inc.
u.jp/index.php?lang=en&mode=c&id=1)
SIJ 3015 EPIGENETICS AND RNA BIOLOGY

SIJ 3013 NATURAL PRODUCT BIOCHEMISTRY AND This course introduces a new field in genetics known as
DRUG DISCOVERY
epigenetics. It will cover topics involving DNA methylation
This course is designed to provide an overview to the field and histone modification and how it controls gene
expression. It will also cover chromatin remodelling and
of natural product and drug discovery. This course covers genomic imprinting. The course will also discuss RNA
the different types of natural product and their usages, related biology processes.
positive/negative effects of its usage, important classes of
chemical compounds, mechanism of reaction, methods and
suitable experimental techniques that can be applied to Assessment Methods:
isolate and identify bioactive component. Drug discovery Continuous Assessment: 40%
component will emphasis on how to bring a drug from Final Examination: 60%
concept to market, introduction to drug approval process,
clinical trials, drug safety guidelines, and ethical issues. Medium of Instruction:
Research and development that will lead to the invention of English
potential commercialisable product will also be discussed
using selected example. Main References:
th
1. Snustad. (2017) Principles of genetics. 7 Edition
Assessment Methods: John Wiley
Continuous Assessment: 40% 2. Devlin. (2013) Textbook of biochemistry. John Wiley
th
Final Examination: 60% 3. Stryer. (2015) Biochemistry. 8 Edition Freeman
4. Watson. (2012) Molecular biology of the gene.
Medium of Instruction: Pearson/Benjamin Cumming.
English 5. Lewin. (2018) Genes XII. Oxford University Press.

Main References: SIJ 3016 BIOCHEMISTRY OF CANCER
1. Recent Trends in Biotechnology and Therapeutic
Application of Medicinal Plants (2013) Mohd Shahid, This course will cover the origins of cancer and the genetic
Anwar Shahzad, Abida Malik, Aastha Sahai; Springer and cellular basis for cancer. It will examine the factors that
2. Drug Discovery and Evaluation: Pharmacological have been implicated in triggering cancers; the intercellular
rd
Assays, 3 ed, edited by H.G. Vogel; Springer interactions involved in cancer proliferation; current
Reference. treatments for cancer and how these are designed; and
future research and treatment directions for cancer therapy.

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