Page 72 - Handbook Bachelor Degree of Science Academic Session 20202021

Faculty of Science Handbook, Academic Session 2020/2021

3. Abbas, A.K. (2014). Basic immunology: functions and SIJ 3010 BIOCHEMICAL PHARMACOLOGY
disorders of the immune system 4th edition.
th
4. Paul, W.E. (2013). Fundamental immunology. 7 This course will examine the molecular basis of drug action
edition. Philadelphia : Wolters Kluwer/Lippincott and explore how cutting edge technology can advance
Williams & Wilkins. pharmacological knowledge, increasing our understanding
5. Molecular and Cellular Mechanisms of Antibody of mechanisms of drug action. The following areas will be
Activity. edited by Falk Nimmerjahn. Springer studied in detail; genetic variability in drug action, protein
eBooks, 2013. structure-activity relationships, receptor-ligand interactions,
signal transduction, biochemical and molecular aspects of
SIJ 3007 MEMBRANE, HORMONE AND CELL G-protein coupled receptors and their signalling
SIGNALLING mechanisms.

This course will discuss the organization and structure of a Assessment Methods:
membrane proteins, their function and the importance to Continuous Assessment: 40%
cell and organisms. Focus will be given on the Final Examination: 60%
transportation processes and cell signalling. For cell
signalling, hormone system will be used as a platform of Medium of Instruction:
discussion, which involve with signalling cells/tissues, the English
target cells/tissues, the mode of transportation, the signal
transduction and the outcome of the signalling.
Main References:
Assessment Methods: 1. Palmer, M., Chan, A., Dieckmann, T., & Honek, J.
Continuous Assessment: 40% (2012). Biochemical-Pharmacology (1st
Final Examination: 60% Edition). WILEY, U.S.
2. Bacq, Z. M. (2014). Fundamental of Biochemistry
Medium of Instruction: Pharmacology, Elsevier.
English 3. Pharmacology 3rd Edition (Lippincott's Illustrated
Reviews) by Richard
Main References: 4. Klaassen, C.D., Casarett, L. and Doull, J. (2013).
1. Molecular Biology of The Cells, 6th edition, Alberts et Casarett and Doull’s Toxicology: The Basic Science
al 2014. of Poisons. McGraw-Hill Prof Med/Tech
2. World of the Cell, 9th edition, Becker et al 2016. 5. Rang, H.P., Dale, M.M., Ritter, J.M. and Flower, R.J.
3. Biochemistry of signal transduction and regulation / (2007). Rang and Dale’s Pharmacology, (6th ed.)
Gerhard Krauss. 5th edition. Gerhard K. (QP517 Churchill Livingstone Elsevier
C45Kra). 2014.
4. An introduction to biological membranes: from SIJ 3011 POST-GENOMIC TECHNOLOGY AND
bilayers to rafts. Stillwell W. ISBN: 9780080931289 ; BIOINFORMATICS
London; Waltham, MA: Elsevier Science,
2013. ScienceDirect® e-Books This course will introduce students to post-genomic era
5. Human Physiology From Cells to Systems 9 edition technologies and how they are used in scientific research.
th
Sherwood et al 2015 The course will focus on three main platforms –
6. The Structure of biological membranes. 2nd edition transcriptomics, proteomics and metabolomics. Students
will be exposed to bioinformatics tools to allow them to
Yeagle P. Boca Raton, FL : CRC Press, 2005. understand, analyse, integrate and correlate data from the
(QH601 Str) three platforms. The use of these technologies in studying
biological systems will also be explored. A brief introduction
to other post-genomic technologies (e.g. lipidomics,
SIJ 3008 ADVANCED MOLECULAR BIOLOGY glycomics, etc) will also be included. Throughout the
course, students will also be introduced to Bioinformatics in
In the first half of the course, students will be thought data analysis and management.
techniques used in the manipulation of DNA and the basics Assessment Methods:
of recombinant DNA technology. Topics covered would Continuous Assessment: 40%
include recombinant technologies, the use of recombinant Final Examination: 60%
technologies in gene manipulation and the basic principles
of the methods used. Medium of Instruction:
English
In the second half of the course, the use of these
approaches in scientific research will be explored. Main References:
1. Scientific journal papers
Assessment Methods: 2. Notes to be provided during lectures
Continuous Assessment: 40% 3. Introducing Proteomics: From concepts to sample
Final Examination: 60% separation, mass spectrometry and data analysis
(2011). Josip Lovric
Medium of Instruction: 4. Transcriptomics: Expression Pattern Analysis (2009).
English Virendra Gomase
5. Metabolomics in Practice: Successful Strategies to
Main References: Generate and Analyze Metabolic Data (2013).
1. Gene Cloning and DNA Analysis: An Introduction (6th Michael Lammerhofer and Wolfram Weckwerth
Edition or later). T.A. Brown
2. Molecular Biology of the Gene (7th Edition or later).
Watson, Baker, Bell, Gann, Levine & Losick
3. Principles of Biochemistry (4th Edition or later). Voet,
Voet & Pratt

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