Page 181 - handbook 20152016

Faculty of Science Handbook, Session 2015/2016

SIK 3012 STEM CELL BIOLOGY Degradation of Health-Risk Compounds / V.P. Singh;
ISBN: 0-444-81977-0 ; Elsevier On ScienceDirect® e-
This lecture series is designed to give the student an in Books
depth understanding of stem cells, their uses in 2. Microbes: Concepts and Applications, Microbes:
regenerative therapies and how stem cells can be the concepts and applications / Prakash S. Bisen,
initiating cells in diseases such as cancer. The course Mousumi Debnath, Godavarthi B.K.S. Prasad. ISBN:
starts with general introduction to stem cell biology which 9780470905944; Hoboken, N.J.: Wiley-Blackwell,
covers definition, characterisation and signalling pathways 2012. On Ebrary e-Books
involved in maintenance of stem cells. The use of stem 3. Microbial Technologies in Advanced Biofuels
cells in regenerative therapies will then be covered, along Production, Microbial Technologies in Advanced
with the generation of the alternative induced pluripotent Biofuels Production /edited by Patrick C. Hallenbeck.
stem cells (iPSC) for use in patient specific therapies and ISBN: — Springer eBooks, 2012
for the study of disease. Finally the course will focus on 4. Bioioaugmentation, Biostimulation and Biocontrol,
stem cells as the initiating cells of cancer and will consider Bioaugmentation, Biostimulation and Biocontrol
the adverse effects of possible genomic instabilities, /edited by Ajay Singh, Nagina Parmar, Ramesh C.
associated with long term culture of human stem cells. Kuhad.
ISBN: — Springer eBooks, 2011
Assessment Methods: 5. Manual of Environmental Microbiology, Manual of
Continuous Assessment: 50% environmental microbiology / editor in chief, Christon
Final Examination: 50% J. Hurst; editors, Ronald L. Crawford [et al.]. ISBN:
9781555813796; 3rd ed.; Washington, D.C.: ASM
Medium of Instruction: Press, c2007. On Ebrary e-Books
English

Soft Skills: SIK 3014 CLINICAL ENZYMOLOGY
CS2, CT2, TS4, LL2
This course encompasses proteins and enzymes
Main References: properties, early enzyme discovery, chemical nature of
1. NIH Stem Cell Primer 2009; ISSCR Primer. enzyme, specificity of enzymes, naming and classification;
2. NIH Early Development; Rossant, Cell 132, 2008. Factors affecting activity of an enzyme; Structural
3. Solter, Nature Rev. Gen. 7, 2006. abnormality of enzymes and expression of isoenzymes,
4. Fuchs, Cell 137, 2009. their clinical significance; Disease and intracellular
5. Morrison & Spradling, Cell 132, 2008. enzyme, basis of diagnostic use; Principle and types of
6. STEMBOOK : http://www.stembook.org/ enzyme assays.

Assessment Methods:
SIK 3013 MICROBIAL BIOPROSPECTING Continuous Assessment: 40%
Final Examination: 60%
This course will prepare the students with knowledge and
practical skill of microbial exploration related to Health Medium of Instruction:
sciences such as microbial diseases & prevention, and English
food/water safety. The topic will include variety of
microbial exploration, its application from laboratory to Soft Skills:
commercialization stage, and world challenges in food CS2, CT3, TS1, LL2
production, therapeutic application in pharmaceutical
industry, bioremediation in agricultural and environmental Main References:
sector, and oil recovery in petroleum industry. This 1. Textbook of Biochemistry with Clinical Correlation.
research-oriented course aims to produce many Thomas Devlin 5th Ed. Wiley-Liss
successful innovators, technological experts and 2. Clinical Biochemistry. An illustrated Colour Text.Gaw
entrepreneurs for future. This course would also be a et al. 3rd. Churchill Livingstone.
model for how universities could transform ideas into real- 3. Clinical Chemistry. Philip D Mayne. 6th Ed. Edward
world innovations beginning with student Arnold. Oxford University Press Inc.
entrepreneurship, technology development, technology 4. Introduction to Protein Structure. Carl Branden and
transfer, and company creation. The outcomes include the John Tooze.Garland Publishing Inc.
creation of educated and successful bioentrepreneurs, the 5. Anatomy and Toxonomy of Protein Structure. Jane. S.
development of new technological innovations, and initiate Richardson. 1981.Adv. Prot. Chem. 34: 167-339
the formation of start-up companies that promote both
societal and economic growth.
SIK 3015 GENETICS AND HUMAN HEALTH
Assessment Methods:
Continuous Assessment: 100% In this course, students will learn the importance of cell
Consisting of; cycle fidelity and genome stability as well as their relation
Case Study/Project Work/Field 70% to the pathophysiology of various genetic diseases
Work/Onsite including cancer. The principles of genetic toxicology and
Presentation 30% the diversity of techniques and tools employed in genetic
toxicology will also be covered in this course. Students will
Medium of Instruction: also learn to appraise the importance and suitability of
English DNA-based technologies for human health improvement.

Soft Skills: Assessment Methods:
CS5, CT7, TS2, LL2, KK4, EM2, LS2 Continuous Assessment: 60%
Final Examination: 40%
Main References:
1. Biotransformations: Microbial Degradation of Health- Medium of Instruction:
Risk Compounds, Biotransformations: Microbial English

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