Page 185 - handbook 20152016

Faculty of Science Handbook, Session 2015/2016

4. Watson. (2012) Molecular biology of the gene.
Soft Skills: Pearson/Benjamin Cummings
CS3, CT3, LL2 5. Lewin. (2012) Genes VIII. Oxford University Press.

Main References:
1. Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto SIJ 2006 PROTEIN BIOCHEMISTRY
th
Jr and Lubert Stryer (2015). Biochemistry (8 edition).
New York: W.H. Freeman. Levels of protein structures - Primary structure, its
2. Christopher K Mathews, Kensal E van Holde, Dean R importance and its determination; Secondary structures
th
Appling (2012). Biochemistry (4 edition). Pearson and their prediction; Super- secondary structures; Tertiary
Education. structure and forces involved in its stabilization;
th
3. Donald Voet, Judith G. Voet (2011).Biochemistry (4 Quaternary structure; Protein folding and denaturation;
edition) .New York: John Wiley. Protein engineering; Protein purification and
4. Reginald H. Garrett and Charles M. Grisham (2013). characterization.
Biochemistry (5th edition). Brooks/Cole, Cengage
Learning. Assessment Methods:
Continuous Assessment: 40%
Final Examination: 60%
SIJ 2004 METABOLISM AND REGULATION OF AMINO
ACIDS AND NUCLEOTIDES Medium of Instruction:
English
The objectives and content of the course are designed to
provide students with a comprehensive understanding of Soft Skills:
the metabolic pathways involving the amino acids and CT2, CS3, LL2
nucleotides; and the manner by which metabolism is
regulated. This course stresses both the normal metabolic Main References:
function, and why disease states occur if normal metabolic 1. Berg, J.M., Tymoczko, J.L., Stryer, L. & Gatto, Jr., G.J.
th
processes are disrupted. (2012) Biochemistry, 7 ed., W.H. Freeman: New York
th
2. Voet D. & Voet J.G. (2011) Biochemistry, 4 ed., John
Assessment Methods: Wiley: New York
Continuous Assessment: 40% 3. Mathews C.K., van Holde K.E., Appling, D.R. &
th
Final Examination: 60% Anthony-Cahill, S.J. (2013) Biochemistry, 4 ed.,
Pearson: Ontario
Medium of Instruction: 4. Nelson, D.L. & Cox M.M. (2013) Lehninger Principles
th
English of Biochemistry, 6 ed., W.H. Freeman: New York
5. Tayyab S. & Boyce A.N. (2006) A Journey from Amino
Soft Skills: Acids to Proteins, University Malaya Press: Kuala
CS3, CT3, LL2 Lumpur

Main References:
1. Nelson, D.L. and Cox, M.M., W.H. (2013) Lehninger: SIJ 2007 ENZYMES: MECHANISM AND CONTROL
Principles of Biochemistry 6th ed., Freeman and
Company (New York). Enzymes as catalysts - Activation energy and biocatalysis;
2. Devlin, T.M (2011). Textbook of Biochemistry with Enzyme specificity; Enzyme kinetics - Effect of enzyme
Clinical Correlations 7th ed.John Wiley & Sons, Inc. concentration, substrate concentration, pH and
(New York). temperature on reaction velocity; Michaelis-Menten
equation and linear transformations; Enzyme inhibitions -
Competitive, Noncompetitive, Uncompetitive and
SIJ 2005 MOLECULAR BIOLOGY Irreversible inhibitions; Active site mapping and
intermediate detection; Enzyme mechanisms with special
This course explains the biosynthesis of Nucleic Acid, reference to lysozyme and chymotrypsin; Enzyme
DNA and RNA. Replication process, trancription and regulation - Zymogen activation, Covalent modification,
translation are also explained in detail. This course also Physiological control and Allosteric regulation; Bi-
covers mutation and how the cells carry out DNA repair; substrate reactions; Catalytic antibodies; Ribozymes
various genetic process such gene recombination anf
transposition; chromosamal inheritance versus Assessment Methods:
ectrachromosamal inheritance. Continuous Assessment : 40%
Final Examination : 60%
Assessment Methods:
Continuous Assessment: 40% Medium of Instruction:
Final Examination: 60% English

Medium of Instruction: Soft Skills:
English CT3, CS3, LL2

Soft Skills: Main References:
CT3, LL2 1. Berg, J.M., Tymoczko, J.L., Stryer, L. & Gatto, Jr., G.J.
th
(2012) Biochemistry, 7 ed., W.H. Freeman: New York
th
Main References: 2. Voet D. & Voet J.G. (2011) Biochemistry, 4 ed., John
Wiley: New York
th
1. Snustad. (2012) Principles of genetics. 7 Edition 3. Mathews C.K., van Holde K.E., Appling, D.R. &
John Wiley Anthony-Cahill, S.J. (2013) Biochemistry, 4 ed.,
th
2. Devlin. (2013) Textbook of biochemistry. John Wiley Pearson: Ontario
3. Stryer. (2012) Biochemistry. Freeman
4. Price N.C. & Stevens, L. (1999) Fundamentals of
rd
Enzymology, 3 ed. Oxford University Press
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