Page 190 - handbook 20152016

Faculty of Science Handbook, Session 2015/2016

4. Advances in Biochemical
Engineering/Biotechnology, 135 (2013) Assessment Methods:
Yellow Biotechnology I. Insect Biotechnologie in Continuous Assessment: 40%
Drug Discovery and Preclinical Research. Eds. Final Examination: 60%
Andreas Vilcinskas. Springer-Verlag Berlin
Heidelberg. ISBN 978-3-642-39862 Medium of Instruction:
5. Basic of Biosciences Agriculture from Nagoya English
University –
OpenCourseWare (http://ocw.nagoya- Soft Skills:
u.jp/index.php?lang=en&mode=c&id=1) CS2, CT3,TS1, LL2
OpenCourseWare (http://ocw.nagoya-
u.jp/index.php?lang=en&mode=c&id=1) Main References:
1. Physical Biochemistry: Principles and Applications.
2000. David Sheehan. Wiley .
SIJ 3013 NATURAL PRODUCT BIOCHEMISTRY AND 2. Introduction to Protein Structure. Carl Branden and
DRUG DISCOVERY John Tooze.Garland Publishing Inc.

This course is designed to provide an overview to the field
of natural product and drug discovery. This course covers SIJ 3015 EPIGENETICS AND RNA BIOLOGY
the different types of natural product and their usages,
positive/negative effects of its usage, important classes of This course introduces a new field in genetics known as
chemical compounds, mechanism of reaction, methods epigenetics. It will cover topics involving DNA methylation
and suitable experimental techniques that can be applied and histone modification and how it controls gene
to isolate and identify bioactive component. Drug expression. It will also cover chromatin remodelling and
discovery component will emphasis on how to bring a drug genomic imprinting. The course will also discuss RNA
from concept to market, introduction to drug approval related biology processes.
process, clinical trials, drug safety guidelines, and ethical
issues. Research and development that will lead to the Assessment Methods:
invention of potential commercialisable product will also Continuous Assessment: 40%
be discussed using selected example. Final Examination: 60%

Assessment Methods: Medium of Instruction:
Continuous Assessment: 40% English
Final Examination: 60%
Soft Skills:
Medium of Instruction: CT3, LL2
English
Main References:
th
Soft Skills: 1. Snustad. (2012) Principles of genetics. 7 Edition
CT3, LL2 John Wiley
2. Devlin. (2013) Textbook of biochemistry. John Wiley
Main References: 3. Stryer. (2012) Biochemistry. Freeman
1. Recent Trends in Biotechnology and Therapeutic 4. Watson. (2012) Molecular biology of the gene.
Application of Medicinal Plants (2013) Mohd Shahid, Pearson/Benjamin Cumming.
Anwar Shahzad, Abida Malik, Aastha Sahai; Springer 5. Lewin. (2012) Genes VIII. Oxford University Press.
2. Drug Discovery and Evaluation: Pharmacological
rd
Assays, 3 ed, edited by H.G. Vogel; Springer
Reference. SIJ 3106 BIOCHEMISTRY OF CANCER
3. Bioactive Natural Products – Detection, Isolation and
Structural Determination (2007), Steven M. Colegate, This course will cover the origins of cancer and the
Russell J. Molyneux; CRC Press genetic and cellular basis for cancer. It will examine the
nd
4. Natural Products from Plants (2006) 2 ed. Leland J factors that have been implicated in triggering cancers; the
Cseke, Ara Kirakosyan, Peter B Kaufman, Sara L intercellular interactions involved in cancer proliferation;
Warber, James A Duke, Harry L Brielmann; Taylor & current treatments for cancer and how these are
Francis designed; and future research and treatment directions for
5. Natural Product Chemistry for Drug Discovery (2009), cancer therapy.
Anthony D Buss, Mark S Butler; RSC Publishing
Assessment Methods:
Continuous Assessment: 40%
SIJ 3014 MOLECULAR STRUCTURAL BIOLOGY Final Examination: 60%

The course will introduce to students the structure of Medium of Instruction:
proteins at all levels, and how this relates to function. A English
non-mathematical introduction of the basic principle of X-
ray crystallography and other techniques used in structural Soft Skills:
studies. Nuclear magnetic resonance (NMR) is the second CS3, CT3, LL3
most important technique for determining the three-
dimensional structure of macromolecules. Electron Main References:
Microscopy (EM) is a technique that is complementary to 1. Robert A. Weinberg (2013). The Biology of Cancer.
X-ray crystallography as it enables the study of non- Garlend Science.
crystalline, very large or transient macromolecular 2. Kleinsmith LJ (2006). Principles of Cancer Biology.
structures. This course also introduces some Pearson.
methodologies for protein purification for structural
studies. It also examines the importance of protein-protein 3. Bronchud, MH. (2004). Principles of Molecular
interactions and some techniques used for the study. Oncology (2nd Ed). Humana Press, New Jersey.

182