Page 189 - handbook 20152016

Faculty of Science Handbook, Session 2015/2016

6. The Structure of biological membranes. 2nd edition SIJ 3011 POST-GENOMIC TECHNOLOGY &
Yeagle P. Boca Raton, FL : CRC Press, 2005. BIOINFORMATICS
(QH601 Str)
7. This course will introduce students to post-genomic era
technologies and how they are used in scientific research.
The course will focus on three main platforms –
SIJ 3008 ADVANCED MOLECULAR BIOLOGY transcriptomics, proteomics and metabolomics. Students
will be exposed to bioinformatics tools to allow them to
In the first half of the course, students will be thought understand, analyse, integrate and correlate data from the
techniques used in the manipulation of DNA and the three platforms. The use of these technologies in studying
basics of recombinant DNA technology. Topics covered biological systems will also be explored. A brief
would include recombinant technologies, the use of introduction to other post-genomic technologies (e.g.
recombinant technologies in gene manipulation and the lipidomics, glycomics, etc) will also be included.
basic principles of the methods used. Throughout the course, students will also be introduced to
In the second half of the course, the use of these Bioinformatics in data analysis and management.
approaches in scientific research will be explored.
Assessment Methods:
Assessment Methods: Continuous Assessment: 40%
Continuous Assessment: 40% Final Examination: 60%
Final Examination: 60%
Medium of Instruction:
Medium of Instruction: English
English
Soft Skills:
Soft Skills: CS3, CT3, TS2, LL2
CS3, CT3, TS2, LL2
Main References:
Main References: 1. Scientific journal papers
1. Gene Cloning and DNA Analysis: An Introduction (6th 2. Notes to be provided during lectures
Edition or later). T.A. Brown 3. Introducing Proteomics: From concepts to sample
2. Molecular Biology of the Gene (7th Edition or later). separation, mass spectrometry and data analysis
Watson, Baker, Bell, Gann, Levine & Losick (2011). Josip Lovric
3. Principles of Biochemistry (4th Edition or later). Voet, 4. Transcriptomics: Expression Pattern Analysis
Voet & Pratt (2009). Virendra Gomase
5. Metabolomics in Practice: Successful Strategies to
Generate and Analyze Metabolic Data (2013).
SIJ 3010 BIOCHEMICAL PHARMACOLOGY Michael Lammerhofer and Wolfram Weckwerth

This course will examine the molecular basis of drug
action and explore how cutting edge technology can SIJ 3012 APPLIED BIOCHEMISTRY AND
advance pharmacological knowledge, increasing our BIOTECHNOLOGY
understanding of mechanisms of drug action. The
following areas will be studied in detail; genetic variability The course introduces principles of fermentation including
in drug action, protein structure-activity relationships, upstream and downstream processes. Enzyme
receptor-ligand interactions, signal transduction, technology in industry and in non-aqueous media.
biochemical and molecular aspects of G-protein coupled Biotechnological approaches for pest management.
receptors and their signalling mechanisms. Management of resistance in transgenic insects towards
GMO plants. The course also examines some effective
Assessment Methods: methods of extraction, purification and quality criteria of
Continuous Assessment: 40% palm oil. The food and non-food uses of palm oil as a
Final Examination: 60% consequence of modifications (chemical, physical,
enzymatic, selective breeding and genetic engineering) of
Medium of Instruction: palm oil will be discussed.
English
Assessment Methods:
Soft Skills: Continuous Assessment: 40%
CS3, CT3, LL2 Final Examination: 60%

Main References: Medium of Instruction:
1. Palmer, M., Chan, A., Dieckmann, T., & Honek, J. English
(2012). Biochemical-Pharmacology (1st
Edition). WILEY, U.S.
2. Bacq, Z. M. (2014). Fundamental of Biochemistry Soft Skills:
Pharmacology, Elsevier. CS3, CT3, LL2
3. Pharmacology 3rd Edition (Lippincott's Illustrated
Reviews) by Richard Main References:
4. Klaassen, C.D., Casarett, L. and Doull, J. (2013). 1. Rosenberg E., DeLong E.F., Lory S., Stackebrandt
Casarett and Doull’s Toxicology: The Basic Science E., Thompson F. (eds) (2013)
of Poisons. McGraw-Hill Prof Med/Tech The Prokaryotes: Prokaryotic Physiology and
5. Rang, H.P., Dale, M.M., Ritter, J.M. and Flower, R.J. 2. Biochemistry, 4th ed. Springer e-Books.
Yukawa H., Inui M. (eds) (2013) Corynebacterium
(2007). Rang and Dale’s Pharmacology, (6th ed.) glutamicum: Biology and Biotechnology. Springer e-
Churchill Livingstone Elsevier
Books.
3. Chen H. (2013) Modern solid state fermentation:
Theory and Practice. Springer e-Books.
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