Page 157 - handbook 20162017
P. 157

Faculty of Science Handbook, Session 2016/2017




               Soft Skills                                      SIL 3008  HUMAN GENETICS
               CS3, CT3, TS3, LL2
                                                                This  course  starts  by  looking  at  the  content  and
               Main References:                                 organisation of the human genome. It involves describing
               1. Krauss,  et  al.  Biochemistry  of  signal  transduction  and  the  gene-related  sequences (genes,  introns,  exons,
                 regulation. Third Edition, Wiley.              regulatory  regions,  pseudogenes  etc) and  non-gene-
               2. Other text books will be referred to.         related  sequences (unique  to  highly  repetitive  classes).
                                                                The  student  is  then  introduced  to  the  Human  Genome
                                                                Project  and  the  processes  involved.  It  includes  physical
               SIL 3006  DEVELOPMENTAL GENETICS                 and  genetic  mapping.  The  second  part  will  focus  on  the
                                                                methods  of  medical  genetic  research,  with  old  and  new
               This course focuses on concepts and understanding of  techniques.  This  includes  functional  cloning,  positional
               developmental  biology  with  an  emphasis  on  molecular  cloning  and  candidate  gene  approaches  (functional
               genetics.  The  topics  covered are:  overview  of  animal  candidacy,  positional  candidacy,  mutation  screening
               development,  early  stages  of  embryonic  development,  methods).  At  the  end  of  the  course,  students  will  be
               basic concept in developmental genetics,  regulation and  familiarised   with   current   issues   and   research
               differential  gene  expression,  molecular  genetics  of  technologywhich  include  SNP  analysis,  microarray  and
               pattern formation in Drosophila, development fate of each  proteomics.
               cell in C. elegens, sex determination in yeast, Drosophila
               and mammals, genetic specification of floral organ identity  Assessment Methods:
               Arabidopsis, stem cell, and ethical issues.      Continuous Assessment:  40%
                                                                Final Examination:  60%
               Assessment Methods:
               Continuous Assessment:  40%                      Medium of Instruction:
               Final Examination:  60%                          English

               Medium of Instruction:                           Soft Skills
               English                                          CS3, CT3, TS3, LL2
               Soft Skills                                      Main References:
               CS3, CT2, TS3, LL2                               1.  Human Molecular Genetics (Strachan & Read)
                                                                2.  Introduction to Human Genetics (Gustavo Maroni)
               Main References:
               1.  Developmental  biology  (10th  edition).  Scott  F.
                   Gilbert. 2013. Sinauer Associates, Inc.      SIL 3009  EPIGENETICS AND GENE REGULATION
               2.  Principles  of  Development (4th  edition).  Lewis
                   Wolpert  and  Cheryll  Tickle.  2010.  Oxford  University  This course will provide a basic understanding of the role
                   Press.                                       of epigenetics in gene regulation. Topics will include
               3.  Molecular Biology of the Cell (5th edition). Alberts B,  chromatin remodelling, histone modifications, DNA
                   Johnson A, Lewis J, et. al. 2007.  Garland Science.  methylation, the importance of epigenetics in normal
                                                                cellular functions, evidence for epigenetics involvement in
                                                                disease.
               SIL 3007  MOLECULAR BIOLOGY OF PLANTS
                                                                Assessment Methods:
               Introduction to basic principles and current advancements  Continuous Assessment:  40%
               in plant molecular biology. This course covers theoretical  Final Examination:  60%
               and  practical  aspects  that  form  the  bases  of  current
               approaches  in  plant  improvement  and  biotechnology,  Medium of Instruction:
               including genetic engineering. Lectures include: structure,  English
               organisation  and  regulation  of  plant  genes  and  cell
               signalling in plant cells; molecular biology of plastids and  Soft Skills
               chloroplasts;   organisation   of   mitochondrial   DNA;  CS4, CT2, TS3, LL3
               molecular  biology  of  nitrogen  metabolism;  molecular
               biology  of  development;  cell  signalling,  molecular  plant-  Main References:
               pathogen interactions, marker assisted breeding and plant  1. Epigenetics,  C.  David  Allis,  Thomas  Jenuwein,  and
               genomics. Related practicals will be given.        Danny Reinberg (2007) Cold Spring Harbor Laboratory
                                                                  Press
               Assessment Methods:                              2. Epigenetics,  Lyle    Armstrong  (2014)  Garland  Science
               Continuous Assessment:  40%                        group
               Final Examination:  60%                          3. Cancer  Epigenetics,  Edited  by  Trygve  Tollefsbol
                                                                  (2009).CRC press, Taylor & Francis group
               Medium of Instruction:
               English                                          SIL 3010  GENOME ANALYSIS

               Soft Skills                                      This course looks into the various approaches and
               CS3, CT3, TS3, LL2                               technologies that can be employed in answering research
                                                                questions and contribute towards the development of field
               Main References:                                 of genetics. The course will also discuss the strength and
               1.  Buchanan, Grusseim and Jones (2006) Biochemistry  weaknesses of each of these technologies, and underlines
                   and MolecularBiology of Plants, Pbls. John Wiley and  the limitations on using these technologies.
                   sons (UK) ISBN 09430088399.
               2.  Genes IX, Benjamin Lewin (2007)              Assessment Methods:
               3.  Information in Spectrum                      Continuous Assessment:  40%
                                                                Final Examination:  60%


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