Page 158 - handbook 20162017

Faculty of Science Handbook, Session 2016/2017

Medium of Instruction: Disease 4th edition Charles A. Janeway, Paul
English Travers, Mark Walport and J Donald Capra
4. The Biology of Cancer. Robert A.Weinberg (2006).
Soft Skills Garland Science Textbooks
CS4, CT3, LL2 5. Journals
Main References:
1. Genome Analysis and Bioinformatics: A Practical SIL 3013 GENETICS AND BIOTECHNOLOGY OF
Approach (2009), Sharma, T. R. VIRUSES
2. Bioinformatics: Sequence and Genome Analysis
(2006), David Mount. This course will involve theoretical and practical skills
3. Analysis of Genes and Genomes (2004), Richard J. related to the genetics and the biotechnological
Reece. application of viruses. Topics will include the biology and
genetics of plant, animal and medically important viruses
and their importance in human lives and activities. Virus
SIL 3011 APPLICATIONS OF RECOMBINANT DNA life cycles and diversity will be compared and discussed
TECHNOLOGY together with the mechanisms of transmission and control,
especially related to medicine and agriculture. The use of
This is an advanced course covering applications of viruses and viral genes in biotechnology ranging from
recombinant DNA technology to medicine, agriculture, research and therapeutic use to applications in agriculture
industry and research. Health care: diagnostics for and industry will also be discussed.
infectious and genetic disease, gene therapy, vaccine
development, RNAi. Agriculture: Transgenic plant Assessment Methods:
technology, transgenic mitigation. Forensic: genetic Continuous Assessment: 40%
means of identification. Industrial and Pharmceutical: Final Examination: 60%
various eukaryotic production systems (yeast, insect,
plant, mammalian), prokaryotic production (E.coli). Medium of Instruction:
Research: gene discovery and isolation, mutagenesis, English
proof of gene function, development of new technologies
(across many fields). Soft Skills
CS4, CT3, TS4, LL3
Assessment Methods:
Continuous Assessment: 40% Main References:
Final Examination: 60% 1. Structure and Physics of Viruses: An Integrated
Textbook Series: Subcellular Biochemistry, Vol. 68
Medium of Instruction: Mateu, Mauricio G. (Ed.) 2013, Springer. ISBN 978-
English 94-007-6552-8 2.
2. Understanding Viruses (Second Edition)Teri Shors
Soft Skills (Ed), 2013. Jones and Bartlett. ISBN-13:
CS3, CT3, TS3, LL2 9781449648923
3. Review papers and journal articles will be supplied
Main References: via course webpage
1. Molecular Biotechnology, principles and applications
of recombinant DNA 4th edition. Glick BR & JJ
Pasternak 2009 (ASM Press) SIL 3014 ADVANCED IMMUNOGENETICS
2. Other recommended materials during lectures
The course gives an understanding of the importance of
the failure and deficiency of the immune system in
SIL 3012 CANCER AND TUMORIGENESIS providing protection. The introduction will focus on
various major components of the immune system and in
The course gives an understanding on cancer and why it situations when it fails in its function as a result in
is seen as a much feared disease worldwide. The initial deficiency of its various components, and the different
development and treatment of cancer will be discussed. A resulting manifestation in the host. These resulting
current review will be given from up-to-date journal immune failure diseases will be discussed: 1. The
papers. This course is most relevant to a genetics student, importance of a balance between tolerance and
as various evidence points to cancer as having a genetic autoimmunity; 2. In certain situation, when cells do not
risk factor that can transform cells from a benign to a respond in the correct manner to growth, resulting in
cancerous state. tumour or cancer. 3. The importance and understanding of
transplant immunology as a cure for certain diseases with
Assessment Methods: organ or cell function failures. 4. The undesired effects
Continuous Assessment: 40% resulting from reactions of effector molecules in
Final Examination: 60% hypersensitivity or allergy. 5. The inability of the immune
system to protect the host from various congenital and
Medium of Instruction: acquired (such as AIDS) immunodeficiency diseases. 6.
English The current therapeutic status and protection with a focus
on vaccines for the undesired immune responses.
Soft Skills
CS3, CT3, TS2, LL2 Assessment Methods:
Continuous Assessment: 40%
Main References: Final Examination: 60%
1. Immunology 5th edition Richard A. Goldsby, Thomas
J. Kindt, Barbara A. Osborne and Janis Kuby Medium of Instruction:
2. Cellular and Molecular Immunology 7th edition Abul English
K. Abbas, Andrew H. Lichtman & Shiv Pillai
3. Immunobiology: The Immune System in Health and

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