Page 186 - handbook 20162017

Faculty of Science Handbook, Session 2016/2017

7.R. A. Henderson, The mechanisms of reactions at Molecular Approach to Thermodynamics
transition metal sites, Oxford Science Publications, The fundamentals of statistical mechanics from the
1993. definitions of molecular interactions giving a set of energy
levels for N-molecule systems. Statistical treatment to
obtain a distribution of the most probable energy
SIC3002 ORGANIC CHEMISTRY III configuration or Boltzmann distribution. Introduction to
partition function of molecules containing all the
Brief introduction to organic synthesis: disconnections and information on N-molecule systems. Ensemble concept,
retrosynthetic analysis; incorporated partition function and its relation to
thermodynamic properties. Intermolecular forces for
Use of compounds incorporating main group elements (B, various systems including liquid and soft matters. Simple
S, Si, P, mainly; and, Sn, Se, Al) in organic functional applications of this method in various chemical problems.
group transformations;
Use of transition metals in C-C bond formation (e.g., Heck, Chemical Kinetics and the Dynamics of Reactions
Suzuki, Stille, Negishi, Sonogashira, Kumada, McMurry, Diffusion controlled reactions. Activated complex theory
etc.); Alkene metathesis. and reactions in solutions. The dynamics of molecular
collisions. The kinetics of fast reactions. Thermodynamics
Stereochemistry: Introduction to asymmetric synthesis, and kinetics of adsorption. Structure, Stability and
axial chirality, importance of enantiopure compounds, reactivity in different state of matter. The properties of non-
chiral pool; selected examples of asymmetric synthesis equilibrium.
including hydroboration, hydride reduction, hydrogenation,
epoxidation, dihydroxylation, and aminohydroxylation, use Assessment Methods:
of chiral auxiliaries in enolate alkylation, crossed-aldol Practical: 25%
additions, and Diels-Alder cycloaddition, etc. Continuous assessment: 15%
Final examination: 60%
Selected total syntheses of biologically-active natural
products of contemporary significance (e.g., taxoids;
macrolides, e.g., epothilones; Catharanthus bisindoles; Medium of instruction:
prostanoids; steroids; etc.). English
Physical organic concepts and methods in the Soft skills:
determination of reaction mechanisms: product studies, CT1-3
intermediates, stereochemistry, energetics and kinetics,
isotope effects (non-kinetic and kinetic), and, linear free References:
energy relationships. 1.P. W. Atkins, Physical Chemistry, 9 th ed., Oxford
University Press, New York, 2010
Assessment Methods: 2.P. W. Atkins, Molecular Quantum Mechanics, 5 th ed.,
Practical: 25% Oxford University Press, New York, 2008.
Continuous assessment: 15% 3.J. P. Lowe, Quantum Chemistry, 2 nd ed., Academic
Final examination: 60% Press, New York, 1993.
4.P. W., Atkins, J. de Paula, Physical Chemistry for the
Medium of instruction: Life Sciences, Oxford University Press, New York, 2006.
English 5. D. Deanin, Polymer Structure, Properties and
Application. Cahners Books, Boston, 1972.
Soft skills: 6.W. Hu, and A. C. Shi, Understanding Soft Condensed
CT1-3 Matter Via Modeling and Computation, Series in Soft
Condensed Matter - Vol. 3. World Scientific Publishing,
References: Singapore, 2001.
1.Francis A. Carey and Richard J. Sundberg, Advanced 7.R. A. L. Jones, Soft condensed matter, Oxford
Organic Chemistry, Part B: Reactions and Synthesis, 4 . University Press, New York, 2002.
th
ed., Plenum Press, New York & London, 2002.
2.E. L. Eliel, S. H. Wilen, L. M. Mander, Stereochemistry
of Organic Compounds, John Wiley & Sons Canada, SIC3004 PROJECT
Ltd., 1994.
3.T. H. Lowry, K. S. Richardson, Mechanism and Theory Students will carry out project works related to the BSc.
in Organic Chemistry, 3 rd ed., Benjamin-Cummings Programme. This course is to be carried out during final
Publishing Company, 1987. semester (1 whole semester). Detailed information about
4.J. M. Harris and C. C. Wamser, Fundamentals of this course can be downloaded from the Department’s
Organic Reaction Mechanisms, Wiley & Sons, 1976. website.
5.N. Isaacs, Physical Organic Chemistry, 2 nd ed., Prentice
Hall, 1996. Assessment Methods:
Continuous assessment: 100%
SIC3003 PHYSICAL CHEMISTRY III Medium of instruction:
English
Molecular Quantum Mechanics
Approximate methods: variational method and time Soft skills:
independent Perturbation theory; Electronic structure of CS1-3, CT1-3, LL1-2, EM1-2
molecules: Born-Oppenheimer approximation, molecular
orbital theory, valence-bond theory, Huckel molecular SIC3005 ADVANCED ENVIRONMENTAL CHEMISTRY
orbital theory, electron configuration, Slater determinant,
angular momentum coupling, molecular term symbols, Sources, reactions, transport, effects and fate of major
spin-orbit and other interactions, molecule spectra and pollutants in the environment. Principles of environmental
selection rules; Hartree-Fock self-consistent-field method, monitoring and sampling, sample storage and
other ab initio methods and hybrid systems. pretreatment. Introduction to basic concepts in analytical

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