Page 177 - buku panduan 20192020

Faculty of Science Handbook, Session 2019/2020

Stereochemistry: Introduction to asymmetric synthesis, Chemical Kinetics and the Dynamics of Reactions
axial chirality, importance of enantiopure compounds, Diffusion controlled reactions. Activated complex theory
chiral pool; selected examples of asymmetric synthesis and reactions in solutions. The dynamics of molecular
including hydroboration, hydride reduction, hydrogenation, collisions. The kinetics of fast reactions. Thermodynamics
epoxidation, dihydroxylation, and aminohydroxylation, use and kinetics of adsorption. Structure, Stability and
of chiral auxiliaries in enolate alkylation, crossed-aldol reactivity in different state of matter. The properties of non-
additions, and Diels-Alder cycloaddition, etc. equilibrium.

Selected total syntheses of biologically-active natural Assessment Methods:
products of contemporary significance (e.g., taxoids; Practical: 25%
macrolides, e.g., epothilones; Catharanthus bisindoles; Continuous assessment: 15%
prostanoids; steroids; etc.). Final examination: 60%

Physical organic concepts and methods in the Medium of instruction:
determination of reaction mechanisms: product studies, English
intermediates, stereochemistry, energetics and kinetics,
isotope effects (non-kinetic and kinetic), and, linear free Soft skills:
energy relationships. CT1-3

Assessment Methods: References:
th
Practical: 25% 1. P. W. Atkins, Physical Chemistry, 11 ed., Oxford
Continuous assessment: 15% University Press, New York, 2018
th
Final examination: 60% 2. P. W. Atkins, Molecular Quantum Mechanics, 5 ed.,
Oxford University Press, New York, 2008.
nd
Medium of instruction: 3. J. P. Lowe, Quantum Chemistry, 2 ed., Academic
English Press, New York, 1993.
4. P. W., Atkins, J. de Paula, Physical Chemistry for the
Soft skills: Life Sciences, Oxford University Press, New York, 2006.
CT1-3 5. D. Deanin, Polymer Structure, Properties and
Application. Cahners Books, Boston, 1972.
References: 6. W. Hu, and A. C. Shi, Understanding Soft Condensed
1. Francis A. Carey and Richard J. Sundberg, Advanced Matter Via Modeling and Computation, Series in Soft
Organic Chemistry, Part B: Reactions and Synthesis, 4 . Condensed Matter - Vol. 3. World Scientific Publishing,
th
ed., Plenum Press, New York & London, 2002. Singapore, 2011.
2. E. L. Eliel, S. H. Wilen, L. M. Mander, Stereochemistry 7. R. A. L. Jones, Soft condensed matter, Oxford
of Organic Compounds, John Wiley & Sons Canada, University Press, New York, 2002.
Ltd., 1994.
3. T. H. Lowry, K. S. Richardson, Mechanism and Theory
rd
in Organic Chemistry, 3 ed., Benjamin-Cummings SIC3004 PROJECT
Publishing Company, 1987.
4. J. M. Harris and C. C. Wamser, Fundamentals of Students will carry out project works related to the BSc.
Organic Reaction Mechanisms, Wiley & Sons, 1976. Programme. This course is to be carried out during final
nd
5. N. Isaacs, Physical Organic Chemistry, 2 ed., Prentice semester (1 whole semester). Detailed information about
Hall, 1996. this course can be downloaded from the Department’s
6. S. Warren; P. Wyatt, Workbook for Organic website.
nd
Synthesis: The Disconnection Approach, 2 ed., John
Wiley & Sons, Ltd.: United Kingdom, 2009. Assessment Methods:
Continuous assessment: 100%

SIC3003 PHYSICAL CHEMISTRY III Medium of instruction:
English
Molecular Quantum Mechanics
Approximate methods: variational method and time Soft skills:
independent Perturbation theory; Electronic structure of CS1-3, CT1-3, LL1-2, EM1-2
molecules: Born-Oppenheimer approximation, molecular
orbital theory, valence-bond theory, Huckel molecular SIC3005 ADVANCED ENVIRONMENTAL CHEMISTRY
orbital theory, electron configuration, Slater determinant,
angular momentum coupling, molecular term symbols, Sources, reactions, transport, effects and fate of major
spin-orbit and other interactions, molecule spectra and pollutants in the environment. Principles of environmental
selection rules; Hartree-Fock self-consistent-field method, monitoring and sampling, sample storage and
other ab initio methods and hybrid systems. pretreatment. Introduction to basic concepts in analytical
chemistry and chemical equilibrium. Introduction to major
Molecular Approach to Thermodynamics analytical techniques for environmental analysis, including
The fundamentals of statistical mechanics from the spectroscopic and chromatographic methods. Data
definitions of molecular interactions giving a set of energy treatment. Quality control and quality assurance.
levels for N-molecule systems. Statistical treatment to
obtain a distribution of the most probable energy Environmental Management
configuration or Boltzmann distribution. Introduction to Conflicts between development and environment.
partition function of molecules containing all the Sustainable development.
information on N-molecule systems. Ensemble concept, Environmental Quality Act (1974). Environmental
incorporated partition function and its relation to management strategies. Environmental Impact
thermodynamic properties. Intermolecular forces for Assessment (EIA). Pollution control.
various systems including liquid and soft matters. Simple
applications of this method in various chemical problems.

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