Page 86 - buku panduan 20192020

Faculty of Science Handbook, Session 2019/2020

Main References: Medium of Instruction:
1. Palmer, M., Chan, A., Dieckmann, T., & Honek, J. English
(2012). Biochemical-Pharmacology (1st
Edition). WILEY, U.S. Soft Skills:
2. Bacq, Z. M. (2014). Fundamental of Biochemistry CS3, CT3, LL2
Pharmacology, Elsevier.
3. Pharmacology 3rd Edition (Lippincott's Illustrated Main References:
Reviews) by Richard 1. Rosenberg E., DeLong E.F., Lory S., Stackebrandt
4. Klaassen, C.D., Casarett, L. and Doull, J. (2013). E., Thompson F. (eds) (2013)
Casarett and Doull’s Toxicology: The Basic Science The Prokaryotes: Prokaryotic Physiology and
of Poisons. McGraw-Hill Prof Med/Tech Biochemistry, 4th ed. Springer e-Books.
5. Rang, H.P., Dale, M.M., Ritter, J.M. and Flower, R.J. 2. Yukawa H., Inui M. (eds) (2013) Corynebacterium
(2007). Rang and Dale’s Pharmacology, (6th ed.) glutamicum: Biology and Biotechnology. Springer e-
Churchill Livingstone Elsevier Books.
3. Lee, Y. K. Microbial Biotechnology: Principles and
Application (3rd ed.). Singapore: World Scientific
SIJ 3011 POST-GENOMIC TECHNOLOGY AND Publishing Company.
BIOINFORMATICS 4. Advances in Biochemical Engineering/
Biotechnology, 135 (2013). Yellow Biotechnology I.
This course will introduce students to post-genomic era Insect Biotechnologie in Drug Discovery and
technologies and how they are used in scientific research. Preclinical Research. Eds. Andreas Vilcinskas.
The course will focus on three main platforms – Springer-Verlag Berlin Heidelberg. ISBN 978-3-642-
transcriptomics, proteomics and metabolomics. Students 39862
will be exposed to bioinformatics tools to allow them to 5. Basic of Biosciences Agriculture from Nagoya
understand, analyse, integrate and correlate data from the University –OpenCourseWare (http://ocw.nagoya-
three platforms. The use of these technologies in studying u.jp/index.php?lang=en&mode=c&id=1)
biological systems will also be explored. A brief OpenCourseWare (http://ocw.nagoya-
introduction to other post-genomic technologies (e.g. u.jp/index.php?lang=en&mode=c&id=1)
lipidomics, glycomics, etc) will also be included.
Throughout the course, students will also be introduced to
Bioinformatics in data analysis and management. SIJ 3013 NATURAL PRODUCT BIOCHEMISTRY AND
DRUG DISCOVERY
Assessment Methods:
Continuous Assessment: 40% This course is designed to provide an overview to the field
Final Examination: 60% of natural product and drug discovery. This course covers
the different types of natural product and their usages,
Medium of Instruction: positive/negative effects of its usage, important classes of
English chemical compounds, mechanism of reaction, methods
and suitable experimental techniques that can be applied
Soft Skills: to isolate and identify bioactive component. Drug
CS3, CT3, TS2, LL2 discovery component will emphasis on how to bring a drug
from concept to market, introduction to drug approval
Main References: process, clinical trials, drug safety guidelines, and ethical
1. Scientific journal papers issues. Research and development that will lead to the
2. Notes to be provided during lectures invention of potential commercialisable product will also
3. Introducing Proteomics: From concepts to sample be discussed using selected example.
separation, mass spectrometry and data analysis
(2011). Josip Lovric Assessment Methods:
4. Transcriptomics: Expression Pattern Analysis Continuous Assessment: 40%
(2009). Virendra Gomase Final Examination: 60%
5. Metabolomics in Practice: Successful Strategies to
Generate and Analyze Metabolic Data (2013). Medium of Instruction:
Michael Lammerhofer and Wolfram Weckwerth English

Soft Skills:
SIJ 3012 APPLIED BIOCHEMISTRY AND CT3, LL2
BIOTECHNOLOGY
Main References:
The course introduces principles of fermentation including 1. Recent Trends in Biotechnology and Therapeutic
upstream and downstream processes. Enzyme Application of Medicinal Plants (2013) Mohd Shahid,
technology in industry and in non-aqueous media. Anwar Shahzad, Abida Malik, Aastha Sahai; Springer
Biotechnological approaches for pest management. 2. Drug Discovery and Evaluation: Pharmacological
rd
Management of resistance in transgenic insects towards Assays, 3 ed, edited by H.G. Vogel; Springer
GMO plants. The course also examines some effective Reference.
methods of extraction, purification and quality criteria of 3. Bioactive Natural Products – Detection, Isolation and
palm oil. The food and non-food uses of palm oil as a Structural Determination (2007), Steven M. Colegate,
consequence of modifications (chemical, physical, Russell J. Molyneux; CRC Press
enzymatic, selective breeding and genetic engineering) of 4. Natural Products from Plants (2006) 2 ed. Leland J
nd
palm oil will be discussed. Cseke, Ara Kirakosyan, Peter B Kaufman, Sara L
Warber, James A Duke, Harry L Brielmann; Taylor &
Assessment Methods: Francis
Continuous Assessment: 40% 5. Natural Product Chemistry for Drug Discovery (2009),
Final Examination: 60% Anthony D Buss, Mark S Butler; RSC Publishing

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