Page 92 - Handbook Bachelor Degree of Science Academic Session 20202021

Faculty of Science Handbook, Academic Session 2020/2021

Main References: Medium of Instruction:
1. Human Molecular Genetics (Strachan & Read) English
2. Introduction to Human Genetics (Gustavo Maroni)
Main References:
1. Molecular Biotechnology, principles and applications
SIL 3009 EPIGENETICS AND GENE REGULATION of recombinant DNA 4th edition. Glick BR & JJ
Pasternak 2009 (ASM Press)
This course will provide a basic understanding of the role 2. Other recommended materials during lectures
of epigenetics in gene regulation. Topics will include
chromatin remodelling, histone modifications, DNA
methylation, the importance of epigenetics in normal SIL 3012 CANCER AND TUMORIGENESIS
cellular functions, evidence for epigenetics involvement in
diseases. The course gives an understanding on cancer and why it is
seen as a much feared disease worldwide. The initial
Assessment Methods: development and treatment of cancer will be discussed. A
Continuous Assessment: 40% current review will be given from up-to-date journal papers.
Final Examination: 60% This course is most relevant to a genetics student, as
various evidence points to cancer as having a genetic risk
Medium of Instruction: factor that can transform cells from a benign to a cancerous
English state.

Main References: Assessment Methods:
1. Epigenetics, C. David Allis, Thomas Jenuwein, and Continuous Assessment: 40%
Danny Reinberg (2007) Cold Spring Harbor Laboratory Final Examination: 60%
Press
2. Epigenetics, Lyle Armstrong (2014) Garland Science Medium of Instruction:
group English
3. Cancer Epigenetics, Edited by Trygve Tollefsbol
(2009).CRC press, Taylor & Francis group Main References:
1. Immunology 5th edition Richard A. Goldsby, Thomas
J. Kindt, Barbara A. Osborne and Janis Kuby
SIL 3010 GENOME ANALYSIS 2. Cellular and Molecular Immunology 7th edition Abul K.
Abbas, Andrew H. Lichtman & Shiv Pillai
This course looks into the various approaches and 3. Immunobiology: The Immune System in Health and
technologies that can be employed in answering research Disease 4th edition Charles A. Janeway, Paul Travers,
questions and contribute towards the development of field Mark Walport and J Donald Capra
of Genetics. The course will also discuss the strength and 4. The Biology of Cancer. Robert A.Weinberg (2006).
weaknesses of each of these technologies, and underlines Garland Science Textbooks
the limitations on using these technologies.

Assessment Methods: SIL 3013 GENETICS AND BIOTECHNOLOGY OF
Continuous Assessment: 100% VIRUSES

Medium of Instruction: This course will involve theoretical and practical skills
English related to the genetics and the biotechnological application
of viruses. Topics will include the biology and genetics of
Main References: plant, animal and medically important viruses and their
1. Genome Analysis and Bioinformatics: A Practical importance in human lives and activities. Virus life cycles
Approach (2009), Sharma, T. R. and diversity will be compared and discussed
2. Bioinformatics: Sequence and Genome Analysis together with the mechanisms of transmission and control,
(2006), David Mount. especially related to medicine and agriculture. The use of
3. Analysis of Genes and Genomes (2004), Richard J. viruses and viral genes in biotechnology ranging from
Reece. research and therapeutic use to applications in agriculture
and industry will also be discussed.

SIL 3011 APPLICATIONS OF RECOMBINANT DNA Assessment Methods:
TECHNOLOGY Continuous Assessment: 40%
Final Examination: 60%
This is an advanced course covering applications of
recombinant DNA technology to medicine, agriculture, Medium of Instruction:
industry and research. Health care: diagnostics for English
infectious and genetic disease, gene therapy, vaccine
development, RNAi. Agriculture: Transgenic plant Main References:
technology, transgenic mitigation. Forensic: genetic means 1. Structure and Physics of Viruses: An Integrated
of identification. Industrial and Pharmceutical: various Textbook Series: Subcellular Biochemistry, Vol. 68
eukaryotic production systems (yeast, insect, plant, Mateu, Mauricio G. (Ed.) 2013, Springer. ISBN 978-
mammalian), prokaryotic production (E.coli). Research: 94-007-6552-8 2.
gene discovery and isolation, mutagenesis, proof of gene 2. Understanding Viruses (Second Edition)Teri Shors
function, development of new technologies (across many (Ed), 2013. Jones and Bartlett. ISBN-13:
fields). 9781449648923
3. Review papers and journal articles will be supplied via
Assessment Methods: course webpage
Continuous Assessment: 40%
Final Examination: 60%

91