Page 104 - buku panduan 20192020

Faculty of Science Handbook, Session 2019/2020

Soft Skills gene expression, transcriptional regulation (DNA binding
CS3, CT2, LL2 domains), and transcriptional regulation through signal
transduction pathway.
Main References:
1. Ridley, M. (2004). Evolution. Blackwell Science. Assessment Methods:
2. Smith, J.M. (1998). Evolutionary Genetics, Oxford Continuous Assessment: 40%
Univ. Press Final Examination: 60%
3. Price P. (1996). Biological Evolution, Saunders
College Publishing. Medium of Instruction:
English

SIL 2006 POPULATION GENETICS Soft Skills
CS3, CT2, LL2
The course is an introduction to the concept of population
genetics for maintenance and importance of genetic Main References:
variation in human, microbes, plants for biodiversity, 1. Snustad, D.P. & Simmons, M.J. (2009). Principles of
agriculture, breeding and fisheries. The course also Genetics. 6th ed. John Wiley.
introduces the statistical programs that are needed for 2. Genetic Analysis and Principles (Brooker).
understanding the principles of population genetics. 3. Other Basic Genetics text books.

Assessment Methods:
Continuous Assessment: 40% SIL 2009 RECOMBINANT DNA TECHNOLOGY
Final Examination: 60%
Introduction to DNA recombinant technology; basic gene
Medium of Instruction: cloning and gene analysis; vector; enzymes; methods of
English DNA restriction and DNA ligation; methods to introduce
foreign DNA into host cells; screening of clones; clones
Soft Skills characterisation; enzymatic manipulation of DNA and
CS3, CT3, TS2, LL3, EM1, LS2 RNA; radioactive and non-radioactive probe labelling;
Southern & Northern hybridisations, colony, plaque and
Main References: dot blotting; radioactive and non-radioactive
1. Mathew b. Hamilton, Wiley Blackwell Publishing hybridisations; plasmid, lambda & M13 phages and
2. Principles of Population Genetics (Background). Hartl cosmid-vector cloning systems, PCR; site directed
DL and Clark AG. Cambridge University Press 3rd mutagenesis and protein engineering; DNA sequencing;
Edition 1997. and gene mapping. Next generation sequencing and
3. Genetics of Populations. Author: Hedrick. PW, Jones & technologies. Practical.
Bartlett Publishing 3rd Edition 2005
Assessment Methods:
Continuous Assessment: 40%
SIL 2007 QUANTITATIVE GENETICS Final Examination: 60%

The course is an introduction to the concept of quantitative Medium of Instruction:
genetics for genetic improvement program. English

Assessment Methods: Soft Skills
Continuous Assessment: 40% CS3, CT2, LL2
Final Examination: 60%
Main References:
Medium of Instruction: 1. Brown TA 2010, Gene Cloning, March 2010, ©2010,
English Wiley-Blackwell
2. Primrose SB, RM Twyman & RW Old 2014, Principles
Soft Skills of Gene Manipulation, 8th ed. Blackwell Sc.
CS3, CT3, TS2, LL3, EM1, LS2 3. Sambrook J. & DW Russell 2001, Molecular Cloning, a
laboratory manual, 3rd ed.CSH Lab Press.
Main References:
1. Falconer, D.S. & Mackay, T.S. (1996). Introduction to
Quantitative Genetics. 4th ed. Wesley Longman. SIL 2010 IMMUNOGENETICS
2. Hartl, T.L. & Jones, E.W. (2005). Essential Genetics.
Jones & Bartlett Publishers. The course gives an understanding on the importance of
3. Stufflebeam, C.E. (1989). Genetics of Domestic the immune system in ensuring immunity. The introduction
Animals. Prentice Hall. is a discussion on the cells involved in the innate and
adaptive systems. An in-depth explanation on the clonal
selection theory, rearrangement process of the
SIL 2008 MOLECULAR GENETICS receptors,T cell thymic education, B cell selection and
production of antibodies/immunoglobulins will be given.
This course includes topics involved in eukaryotic DNA The role of the major histocompatibilty complex in
replication,gene transcription and translation. The topics processing and presentation of antigens, activation and
covered: Eukaryotic genome, C-value paradox, histones signal transduction of T and B cells and importance of
and non-histone proteins, heterochromatin and cytokines regulation in immune responses will be
euchromatin, classes of DNA, DNA replication in discussed. Important immune and effector mechanisms in
eukaryotes, transcription, RNA polymerases I, II and III, inflammation, phagocytosis and complement will be given
gene regulation in eukaryotes, various control and the main focus. The last section of the course will give an
regulatory elements, pre-mRNA processing and overview of how each component signals the downstream
alternative splicing, RNA processing events (rRNA, tRNA, components in a cascade to generate an immune
trans-splicing, RNA-editing), posttranscriptional control of response with the cytokines as regulators, and helper T

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