Page 106 - buku panduan 20192020

Faculty of Science Handbook, Session 2019/2020

SIL 3002 INDUSTRIAL TRAINING IN GENETICS AND receptor, G protein coupled receptors, enzyme linked
MOLECULAR BIOLOGY receptors, non-receptor enzymes in signalling and second
messengers.
The course provides students with an exposure to work at
a diagnostic or research laboratory outside of the Assessment Methods:
university’s environment. Students are able to observe the Continuous Assessment: 40%
application of information from university courses and to Final Examination: 60%
use it in the course of their attachment to these
laboratories. Medium of Instruction:
English
Assessment Methods:
Continuous assessment: 100% Soft Skills
CS3, CT3, TS3, LL2
Medium of Instruction:
English Main References:
1. Krauss, et al. Biochemistry of signal transduction and
Soft Skills regulation. Third Edition, Wiley.
CS3, CT2, TS3, LL2 2. Other text books will be referred to.

SIL 3004 ADVANCED GENETICS SIL 3006 DEVELOPMENTAL GENETICS

Gene mutation, the Luria-Delbrück fluctuation test, the ClB This course focuses on concepts and understanding of
chromosome, the Ames test for mutagenicity, trinucleotide developmental biology with an emphasis on molecular
repeat expansion, DNA repair systems: direct repair, genetics. The topics covered are: overview of animal
nucleotide and base excision repair, mismatch repair, and development, early stages of embryonic development,
recombinational repair, sister chromatid exchange, basic concept in developmental genetics, regulation and
harlequin chromosomes, homologous recombination: the differential gene expression, molecular genetics of
Holliday model, the Meselson-Radding model, and the pattern formation in Drosophila, development fate of each
double-stranded break model, gene conversion, site- cell in C. elegens, sex determination in yeast, Drosophila
specific recombination, transposition: Ds and Ac, and mammals, genetic specification of floral organ identity
transposons: insertion sequence, complex transposon, Arabidopsis, stem cell, and ethical issues.
and composite transposon, transposon tagging, non-
Mendelian inheritance: maternal effect, epigenetic Assessment Methods:
inheritance (dosage compensation and genomic imprinting Continuous Assessment: 40%
- Prader-Willi syndrome and Angelman syndrome, Final Examination: 60%
uniparental disomy: isodisomy and hetrerodisomy), and
extranuclear or cytoplasmic inheritance (maternal Medium of Instruction:
inheritance, pigmentation trait in plants, male-sterility trait, English
petite traits: segregational petite mutants and vegetative
petite mutants - neutral petites and suppressive petites, Soft Skills
chloroplast inheritance in Chlamydomonas, uniparental CS3, CT2, TS3, LL2
inheritance), evolution of the concept of the gene: function
and structure, the complementation test, the cis-trans test, Main References:
homoalleles and heteroalleles, intragenic 1. Developmental biology (10th edition). Scott F.
complementation, limitations on the use of the Gilbert. 2013. Sinauer Associates, Inc.
complementation test. 2. Principles of Development (4th edition). Lewis
Wolpert and Cheryll Tickle. 2010. Oxford University
Assessment Methods: Press.
Continuous Assessment: 40% 3. Molecular Biology of the Cell (5th edition). Alberts B,
Final Examination: 60% Johnson A, Lewis J, et. al. 2007. Garland Science.

Medium of Instruction:
English SIL 3007 MOLECULAR BIOLOGY OF PLANTS

Soft Skills Introduction to basic principles and current advancements
CT3, CS2, LL2 in plant molecular biology. This course covers theoretical
and practical aspects that form the bases of current
Main References: approaches in plant improvement and biotechnology,
1. Principles of Genetics 4th Edition (Snustad and including genetic engineering. Lectures include: structure,
Simmons). Wiley Publications organisation and regulation of plant genes and cell
2. Genetic Analysis and Principles (Brooker) signalling in plant cells; molecular biology of plastids and
3. Other Basic Genetics text books chloroplasts; organisation of mitochondrial DNA;
molecular biology of nitrogen metabolism; molecular
biology of development; cell signalling, molecular plant-
SIL 3005 FROM CELL TO SYSTEM pathogen interactions, marker assisted breeding and plant
genomics. Related practicals will be given.
This is an advanced course covering the following topics
of cellular and molecular biology of eukaryotes: revision of Assessment Methods:
the cell cycle and the molecular basis of cell cycle Continuous Assessment: 40%
regulation, apoptosis pathways, modes of cell signalling, Final Examination: 60%
signalling molecules and their receptors, signal
transduction, signalling pathways, types of cell surface Medium of Instruction:
English

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