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Faculty of Science Handbook, Session 2019/2020




               2.  Wagner, H. and Bladt, S. (1996).  Plant Drug Analysis   SIK 3011    CANCER BIOLOGY
                    nd
                  (2  Ed).  Springer Verlag
               3.  Basic  Tests  for  Pharmaceutical  Substances  (1990),   Topics   taught   encompass   nomenclature;   staging;
                  WHO, Geneva                                   pathology;  the carcinogenesis concept;  classification  and
                                         th
               4.  The  Use  of  Essential  Drugs,  9   Report  of  the  WHO   type  of  carcinogen;  epidemiology;  etiology;  therapy;
                  Expert  Committee  (2000).    Technical  Report  Series   prevention  and  discussion  on  common  cancers  in
                  895                                           Malaysia.
               5.  Flower,  DR.  (2002).    Drug  Design:  Cutting  Edge
                  Approaches. Royal Society of Chemistry, Cambridge.   Assessment Methods:
                                                                Continuous Assessment:   40%
                                                                Final Examination:    60%
               SIK 3009    BASIC HERBAL MEDICINE
                                                                Medium of Instruction:
               The  course  consist  of  the  introduction  to  the  medicinal   English
               plants  and  herbal  medicine,  history  of  medicinal  plants,
               classification of medicinal plants, types and part of herbs   Soft Skills:
               use  as  a  drugs,  medicinal  herbs  system,  drug  herbs   CS2, CT2, LL2
               application, drug herbs preparation, chemical constituents
               of  medicinal  plants,  herbal  medicine  formulation,   Main References:
               development  of  herbal  drugs,  registration  of  herbal   1.  Cooper, G.M. (2009).  The Cell: A Molecular Approach
               medicine.                                           (5  ed.). ASM Press. Washington, D.C.
                                                                    th
                                                                2.  Mendelsohn, J. et al. (2008). The Molecular Basis of
               Assessment Methods:                                 Cancer. Saunders/Elsevier. Philadelphia
               Continuous Assessment:   40%                     3.  Weinberg,  R.A.  (2007).    The  Biology  of  Cancer.
               Final Examination:    60%                           Garland Science. New York.
                                                                4.  King,  R.J.B.  &  Robins,  M.W.  (2006).  Cancer  Biology
                                                                    rd
               Medium of Instruction:                              (3  ed.). Pearson/Prentice Hall, England.
               English                                          5.  Macdonald,  C.H.J.  &  Casson,  F.A.G.  (2004).
                                                                   Molecular Biology of Cancer (2  ed.). BIOS Scientific
                                                                                         nd
               Soft Skills:                                        Publishers. London.
               CS1, CT3, LL2

               Main References:                                 SIK 3012    STEM CELL BIOLOGY
               1.  Edward. P. Claus; Varro. E. Tyler and Lynn. R. (1970)
                  Pharmacognosy 6th edition.                    This  lecture  series  is  designed  to  give  the  student  an  in
               2.  Ethnopharmacology of Medicinal Plants: Asia and the   depth  understanding  of  stem  cells,  their  uses  in
                  Pacific  by  christophe  Wiert,  Totowa,  NJ  :Humana   regenerative  therapies  and  how  stem  cells  can  be  the
                  Press Inc.,2007.; Via: Springer Ebook         initiating  cells  in  diseases  such  as  cancer.  The  course
               3.  Muhamad  Zakaria  and  Mustafa  Ali  Mohd  (1994)   starts with general introduction to stem cell biology which
                  Traditional  Malay  Medicinal  Plants,  Penerbit  Fajar   covers definition, characterisation and signalling pathways
                  Bakti Sdn Bhd.                                involved  in  maintenance  of  stem  cells.  The  use  of  stem
               4.  Christophe wiart (2000) Mecidinal Plants of southeast   cells in regenerative therapies will then be covered, along
                  Asia, Pelanduk Publications.                  with  the  generation  of  the  alternative  induced  pluripotent
               5.  Malaysian  Herbal  Monograph  (1999)  Volume  1,   stem cells (iPSC) for use in patient specific therapies and
                  Published by the Malaysian Monograph committee.     for  the study  of  disease.  Finally the  course  will  focus  on
                                                                stem cells as the initiating cells of cancer and will consider
                                                                the  adverse  effects  of  possible  genomic  instabilities,
               SIK 3010    ANALYTICAL BIOCHEMISTRY              associated with long term culture of human stem cells.

               This  course  covers  chromatography  principles  and   Assessment Methods:
               techniques,  together  with  the  use  of  spectrophotometer,   Continuous Assessment:   50%
               radioimmunoassay and autoanalyser.               Final Examination:    50%

               Assessment Methods:                              Medium of Instruction:
               Continuous Assessment:   40%                     English
               Final Examination:    60%
                                                                Soft Skills:
               Medium of Instruction:                           CS2, CT2, TS4, LL2
               English
                                                                Main References:
               Soft Skills:                                     1. NIH Stem Cell Primer 2009; ISSCR Primer.
               CS2, CT2, LL2                                    2. NIH Early Development; Rossant, Cell 132, 2008.
                                                                3. Solter, Nature Rev. Gen. 7, 2006.
               Main References:                                 4. Fuchs, Cell 137, 2009.
                                                    rd
               1.  Holme,  DJ.  (1998).    Analytical  Biochemistry  (3   Ed).    5. Morrison & Spradling, Cell 132, 2008.
                  Longman, UK                                   6. STEMBOOK : http://www.stembook.org/
               2.  Voet,  Donald  (2004).    Fundamentals  of  Biochemistry
                    nd
                  (2  Ed).  Wiley, New York.
               3.  Pratt,  CW.  (2004).    Essential  Biochemistry.    John   SIK 3013    MICROBIAL BIOPROSPECTING
                  Wiley, New Jersey
                                                                This course will prepare the students with knowledge and
                                                                practical  skill  of  microbial  exploration  related  to  Health
                                                                sciences  such  as  microbial  diseases  &  prevention,  and
                                                                food/water  safety.   The  topic  will  include  variety  of
                                                                microbial exploration,  its application  from  laboratory  to

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