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Faculty of Science Handbook, Session 2017/2018

3. Pratt, CW. (2004). Essential Biochemistry. John Wiley, SIK 3013 MICROBIAL BIOPROSPECTING
New Jersey
This course will prepare the students with knowledge and
practical skill of microbial exploration related to Health
SIK 3011 CANCER BIOLOGY sciences such as microbial diseases & prevention, and
food/water safety. The topic will include variety of
Topics taught encompass nomenclature; staging; microbial exploration, its application from laboratory to
pathology; the carcinogenesis concept; classification and commercialization stage, and world challenges in food
type of carcinogen; epidemiology; etiology; therapy; production, therapeutic application in pharmaceutical
prevention and discussion on common cancers in Malaysia. industry, bioremediation in agricultural and environmental
sector, and oil recovery in petroleum industry. This
Assessment Methods: research-oriented course aims to produce many successful
Continuous Assessment: 40% innovators, technological experts and entrepreneurs for
Final Examination: 60% future. This course would also be a model for how
universities could transform ideas into real-world
Medium of Instruction: innovations beginning with student entrepreneurship,
English technology development, technology transfer, and
company creation. The outcomes include the creation of
Soft Skills: educated and successful bioentrepreneurs, the
CS2, CT2, LL2 development of new technological innovations, and initiate
the formation of start-up companies that promote both
Main References: societal and economic growth.
1. Cooper, G.M. (2009). The Cell: A Molecular Approach
(5 ed.). ASM Press. Washington, D.C. Assessment Methods:
th
2. Mendelsohn, J. et al. (2008). The Molecular Basis of Continuous Assessment: 100%
Cancer. Saunders/Elsevier. Philadelphia Consisting of;
3. Weinberg, R.A. (2007). The Biology of Cancer. Case Study/Project Work/Field 70%
Garland Science. New York. Work/Onsite
4. King, R.J.B. & Robins, M.W. (2006). Cancer Biology Presentation 30%
rd
(3 ed.). Pearson/Prentice Hall, England.
5. Macdonald, C.H.J. & Casson, F.A.G. (2004). Medium of Instruction:
Molecular Biology of Cancer (2 ed.). BIOS Scientific English
nd
Publishers. London.
Soft Skills:
CS5, CT7, TS2, LL2, KK4, EM2, LS2
SIK 3012 STEM CELL BIOLOGY
Main References:
This lecture series is designed to give the student an in 1. Biotransformations: Microbial Degradation of Health-
depth understanding of stem cells, their uses in Risk Compounds, Biotransformations: Microbial
regenerative therapies and how stem cells can be the Degradation of Health-Risk Compounds / V.P. Singh;
initiating cells in diseases such as cancer. The course starts ISBN: 0-444-81977-0 ; Elsevier On ScienceDirect® e-
with general introduction to stem cell biology which covers Books
definition, characterisation and signalling pathways 2. Microbes: Concepts and Applications, Microbes:
involved in maintenance of stem cells. The use of stem cells concepts and applications / Prakash S. Bisen, Mousumi
in regenerative therapies will then be covered, along with Debnath, Godavarthi B.K.S. Prasad. ISBN:
the generation of the alternative induced pluripotent stem 9780470905944; Hoboken, N.J.: Wiley-Blackwell,
cells (iPSC) for use in patient specific therapies and for the 2012. On Ebrary e-Books
study of disease. Finally the course will focus on stem cells 3. Microbial Technologies in Advanced Biofuels
as the initiating cells of cancer and will consider the adverse Production, Microbial Technologies in Advanced
effects of possible genomic instabilities, associated with Biofuels Production /edited by Patrick C. Hallenbeck.
long term culture of human stem cells. ISBN: — Springer eBooks, 2012
4. Bioioaugmentation, Biostimulation and
Assessment Methods: Biocontrol, Bioaugmentation, Biostimulation and
Continuous Assessment: 50% Biocontrol /edited by Ajay Singh, Nagina Parmar,
Final Examination: 50% Ramesh C. Kuhad.
ISBN: — Springer eBooks, 2011
Medium of Instruction: 5. Manual of Environmental Microbiology, Manual of
English environmental microbiology / editor in chief, Christon J.
Hurst; editors, Ronald L. Crawford [et al.]. ISBN:
Soft Skills: 9781555813796; 3rd ed.; Washington, D.C.: ASM
CS2, CT2, TS4, LL2 Press, c2007. On Ebrary e-Books

Main References:
1. NIH Stem Cell Primer 2009; ISSCR Primer. SIK 3014 CLINICAL ENZYMOLOGY
2. NIH Early Development; Rossant, Cell 132, 2008.
3. Solter, Nature Rev. Gen. 7, 2006. This course encompasses proteins and enzymes
4. Fuchs, Cell 137, 2009. properties, early enzyme discovery, chemical nature of
5. Morrison & Spradling, Cell 132, 2008. enzyme, specificity of enzymes, naming and classification;
6. STEMBOOK : http://www.stembook.org/ Factors affecting activity of an enzyme; Structural
abnormality of enzymes and expression of isoenzymes,
their clinical significance; Disease and intracellular enzyme,
basis of diagnostic use; Principle and types of enzyme
assays.

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