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Faculty of Science Handbook, Session 2017/2018




               Main References:                                 Main References:
                1.  Biochemistry, 7 ed (2012); Lubert M Stryer:  1. Nelson, D.L. and Cox, M.M., W.H. (2013) Lehninger:
                               th
                    Macmillan Education.                           Principles  of  Biochemistry  6th  ed.,  Freeman  and
                2.  Textbook of biochemistry with clinical correlations,  Company (New York).
                     th
                    6 ed; Ed by Thomas M Devlin;   John Wiley & Sons  2. Devlin,  T.M  (2011).  Textbook  of  Biochemistry  with
                    Inc (downloadable).                            Clinical  Correlations  7th  ed.John  Wiley  &  Sons,  Inc.
                               th
                3.  Biochemistry; 4 ed,(2011) Voet & Voet, Wiley   (New York).
                4.  Biochemistry; 5 Ed, Garrett & Grisham:
                               th
                    Brooks/Cole Cengage Learning.
                5.  A journey from amino acids to proteins; Saad  SIJ 2005 MOLECULAR BIOLOGY
                    Tayyab & Amru Nasrulhaq Boyce; Uni Malaya
                    Press.                                      This course explains the biosynthesis of Nucleic Acid, DNA
                                                                and RNA. Replication process, trancription and translation
                                                                are  also  explained  in  detail.  This  course  also  covers
               SIJ 2003 ENERGETICS, METABOLISM AND              mutation and how the cells carry out DNA repair; various
                       REGULATION OF CARBOHYDRATE               genetic process such gene recombination anf transposition;
                       AND LIPIDS                               chromosamal   inheritance   versus   ectrachromosamal
                                                                inheritance.
               The students will learn the principles of bioenergetics,  Assessment Methods:
               biosynthesis and catabolism of the primary       Continuous Assessment:  40%
               macromolecules, and regulatory mechanisms involved in  Final Examination:  60%
               intermediary metabolism.
                                                                Medium of Instruction:
               The course encompasses the following topics: (1) Concept  English
               of energy in metabolism and energy production by aerobic
               and  anaerobic  respiration,  and  fermentation;  (2)  Soft Skills:
               Biosynthesis  and  catabolism  of  primary  macromolecules  CT3, LL2
               (carbohydrate,  lipid,  sulphur  compounds);  (3)  Regulation
               and integration of metabolic processes.          Main References:
                                                                1. Snustad. (2012) Principles of genetics. 7 Edition
                                                                                                th
               Assessment Methods:                                 John Wiley
               Continuous Assessment:  40%                      2. Devlin. (2013) Textbook of biochemistry. John Wiley
               Final Examination:    60%                        3. Stryer. (2012) Biochemistry.  Freeman
                                                                4. Watson. (2012) Molecular biology of the gene.
               Medium of Instruction:                              Pearson/Benjamin Cummings
               English                                          5. Lewin. (2012) Genes VIII. Oxford University Press.
               Soft Skills:
               CS3, CT3, LL2                                    SIJ 2006 PROTEIN BIOCHEMISTRY

               Main References:                                 Levels  of  protein  structures - Primary  structure,  its
               1. Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto  importance  and  its  determination;  Secondary  structures
                                                 th
                  Jr and Lubert Stryer (2015). Biochemistry (8 edition).  and their prediction; Super- secondary structures; Tertiary
                  New York: W.H. Freeman.                       structure and forces involved in its stabilization; Quaternary
               2. Christopher K Mathews, Kensal E van Holde, Dean R  structure;  Protein  folding  and  denaturation;  Protein
                                         th
                  Appling (2012). Biochemistry (4 edition). Pearson  engineering; Protein purification and characterization.
                  Education.
               3. Donald Voet, Judith G. Voet (2011).Biochemistry (4 th  Assessment Methods:
                  edition) .New York: John Wiley.               Continuous Assessment:  40%
               4. Reginald H. Garrett and Charles M. Grisham (2013).  Final Examination:  60%
                  Biochemistry (5th edition). Brooks/Cole, Cengage  Medium of Instruction:
                  Learning.                                     English
               SIJ 2004 METABOLISM AND REGULATION OF AMINO      Soft Skills:
                       ACIDS AND NUCLEIC ACIDS                  CT2, CS3, LL2
               The objectives and content of the course are designed to  Main References:
               provide students with a comprehensive understanding of  1. Berg, J.M., Tymoczko, J.L., Stryer, L. & Gatto, Jr., G.J.
               the metabolic pathways involving the amino acids and  (2012) Biochemistry, 7 ed., W.H. Freeman: New York
                                                                                   th
               nucleotides; and the manner by which metabolism is  2. Voet D. & Voet J.G. (2011) Biochemistry, 4 ed., John
                                                                                                 th
               regulated. This course stresses both the normal metabolic  Wiley: New York
               function, and why disease states occur if normal metabolic  3. Mathews C.K., van Holde K.E., Appling, D.R.  &
               processes are disrupted.                            Anthony-Cahill, S.J. (2013) Biochemistry, 4 ed.,
                                                                                                 th
                                                                   Pearson: Ontario
               Assessment Methods:                              4. Nelson, D.L. & Cox M.M. (2013) Lehninger Principles
                                                                                th
               Continuous Assessment:  40%                         of Biochemistry, 6 ed., W.H. Freeman: New York
               Final Examination:    60%                        5. Tayyab S. & Boyce A.N. (2006) A Journey from Amino
                                                                   Acids  to  Proteins,  University  Malaya  Press:  Kuala
               Medium of Instruction:                              Lumpur
               English
               Soft Skills:
               CS3, CT3,  LL2

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