Page 133 - tmp

Faculty of Science Handbook, Session 2017/2018

SIJ 3012 APPLIED BIOCHEMISTRY AND
BIOTECHNOLOGY Main References:
1. Recent Trends in Biotechnology and Therapeutic
The course introduces principles of fermentation including Application of Medicinal Plants (2013) Mohd Shahid,
upstream and downstream processes. Enzyme technology Anwar Shahzad, Abida Malik, Aastha Sahai; Springer
in industry and in non-aqueous media. Biotechnological 2. Drug Discovery and Evaluation: Pharmacological
approaches for pest management. Management of Assays, 3 ed, edited by H.G. Vogel; Springer
rd
resistance in transgenic insects towards GMO plants. The Reference.
course also examines some effective methods of 3. Bioactive Natural Products – Detection, Isolation and
extraction, purification and quality criteria of palm oil. The Structural Determination (2007), Steven M. Colegate,
food and non-food uses of palm oil as a consequence of Russell J. Molyneux; CRC Press
modifications (chemical, physical, enzymatic, selective 4. Natural Products from Plants (2006) 2 ed. Leland J
nd
breeding and genetic engineering) of palm oil will be Cseke, Ara Kirakosyan, Peter B Kaufman, Sara L
discussed. Warber, James A Duke, Harry L Brielmann; Taylor &
Francis
Assessment Methods: 5. Natural Product Chemistry for Drug Discovery (2009),
Continuous Assessment: 40% Anthony D Buss, Mark S Butler; RSC Publishing
Final Examination: 60%
Medium of Instruction: SIJ 3014 MOLECULAR STRUCTURAL BIOLOGY
English
The course will introduce to students the structure of
Soft Skills: proteins at all levels, and how this relates to function. A non-
CS3, CT3, LL2 mathematical introduction of the basic principle of X-ray
crystallography and other techniques used in structural
Main References: studies. Nuclear magnetic resonance (NMR) is the second
1. Rosenberg E., DeLong E.F., Lory S., Stackebrandt most important technique for determining the three-
E., Thompson F. (eds) (2013) dimensional structure of macromolecules. Electron
The Prokaryotes: Prokaryotic Physiology and Microscopy (EM) is a technique that is complementary to X-
Biochemistry, 4th ed. Springer e-Books. ray crystallography as it enables the study of non-
2. Yukawa H., Inui M. (eds) (2013) Corynebacterium crystalline, very large or transient macromolecular
glutamicum: Biology and Biotechnology. Springer e- structures. This course also introduces some
Books. methodologies for protein purification for structural studies.
3. Lee, Y. K. Microbial Biotechnology: Principles and It also examines the importance of protein-protein
Application (3rd ed.). Singapore: World Scientific interactions and some techniques used for the study.
Publishing Company.
4. Advances in Biochemical Assessment Methods:
Engineering/Biotechnology, 135 (2013) Continuous Assessment: 40%
Yellow Biotechnology I. Insect Biotechnologie in Drug Final Examination: 60%
Discovery and Preclinical Research. Eds. Andreas
Vilcinskas. Springer-Verlag Berlin Medium of Instruction:
Heidelberg. ISBN 978-3-642-39862 English
5. Basic of Biosciences Agriculture from Nagoya
University –OpenCourseWare (http://ocw.nagoya- Soft Skills:
u.jp/index.php?lang=en&mode=c&id=1) CS2, CT3,TS1, LL2
OpenCourseWare (http://ocw.nagoya-
u.jp/index.php?lang=en&mode=c&id=1) Main References:
1. Physical Biochemistry: Principles and Applications.
2000. David Sheehan. Wiley .
SIJ 3013 NATURAL PRODUCT BIOCHEMISTRY AND 2. Introduction to Protein Structure. Carl Branden and
DRUG DISCOVERY John Tooze.Garland Publishing Inc.
This course is designed to provide an overview to the field
of natural product and drug discovery. This course covers SIJ 3015 EPIGENETICS AND RNA BIOLOGY
the different types of natural product and their usages,
positive/negative effects of its usage, important classes of This course introduces a new field in genetics known as
chemical compounds, mechanism of reaction, methods and epigenetics. It will cover topics involving DNA methylation
suitable experimental techniques that can be applied to and histone modification and how it controls gene
isolate and identify bioactive component. Drug discovery expression. It will also cover chromatin remodelling and
component will emphasis on how to bring a drug from genomic imprinting. The course will also discuss RNA
concept to market, introduction to drug approval process, related biology processes.
clinical trials, drug safety guidelines, and ethical issues.
Research and development that will lead to the invention of Assessment Methods:
potential commercialisable product will also be discussed Continuous Assessment: 40%
using selected example. Final Examination: 60%
Assessment Methods: Medium of Instruction:
Continuous Assessment: 40% English
Final Examination: 60%
Soft Skills:
Medium of Instruction: CT3, LL2
English
Main References:
Soft Skills: 1. Snustad. (2012) Principles of genetics. 7 Edition
th
CT3, LL2 John Wiley
130