Page 57 - Handbook Bachelor Degree of Science Academic Session 20212022

Faculty of Science Handbook, Academic Session 2021/2022

research technology including SNP, microarray, proteomics
Main References: and NGS technologies.
1. Sharma, T.R. Genome Analysis and
Bioinformatics: A Practical Approach, 2009, Wiley Assessment Methods:
2. Pevsner J. Bioinformatics and Functional Continuous Assessment: 40%
Genomics, 3rd ed, 2015, Wiley Final Examination: 60%
3. Brown T.A. Genomes 4, 4th ed, 2018, Garland
Science Main References:
1. Strachan T. & Read A. Human Molecular
Genetics,4th ed, 2013, Garland Science
SIR2020 GENETICS AND MOLECULAR BIOLOGY 2. Lewis R. Human Genetics, 10th ed, 2015, McGraw
PRACTICAL II Hill
3. Valencia C.A. et al. Next Generation Sequencing
The practical classes emphasize on learning laboratory Technologies in Medical Genetics, 2013, Springer
approaches to DNA, RNA and protein assays requiring
hands-on bench-work and biological data analysis. The
introductory lectura prior to the wet lab covers the theory SIR4001 RESEARCH PROJECT
behind the experiment and some of the techniques. This
practical module focuses on the eukaryotic system in This course is intended to introduce practical aspects of the
animal and plant cells. Techniques will include the principles of Microbiology/ Molecular Genetics. Students
principles of DNA extraction, RNA extraction, protein will be exposed to research methodology in Microbiology/
extraction, Sanger sequencing, multiple sequence Molecular Genetics field, critical scientific thinking, methods
alignment, BLAST, oligonucleotide design; synthesis, for problem solving, research ethics, record keeping,
quantitative polymerase chain reaction analysis, western presentation and scientific writing skills. Students are
blotting, one and two dimensional electrophoresis. Recent required to: 1) write a project proposal and carry out
advances in Genomics analysis will also be briefly taught. literatura review; 2) carry out experiments in the laboratory;
3) analyse data; 4) write a mini thesis; 5) present the results
Assessment Methods: of the research orally.
Continuous Assessment: 100%
Assessment Methods:
Main References: Continuous Assessment: 100%
1. Green M.R. & Sambrook J. Molecular Cloning: A
Laboratory Manual, Three-volume set 4th ed, 2012,
CSH Laboratory Press SIR4002 INDUSTRIAL TRAINING
2. Cold Spring Harbor Protocols
This industrial training module will provide students with
real on-the-job experience and hands on practical skills in
SIR3018 BIOSAFETY AND BIOSECURITY the fields of microbiology and genetics. Students are able
to put into practice the knowledge and skills gathered during
Awareness on the importance of biosafety and biosecurity degree studies in a professional environment during the
that arises within the profession and scientific research of industrial attachment. Students will undergo 16 weeks of
microbiology and genetics. Case studies of biosafety and industrial training in the final semester.
biosecurity and relevant biorisk management will be
discussed. The importance of lab safety and accreditation Assessment Methods:
will also be explored. Continuous Assessment: 100%
Assessment Methods: Main References:
Continuous Assessment: 100% 1. Standard Operating Procedure at industrial
placement.
Main References: 2. Briefing notes from the coordinator.
1. Salerno R. & Gaudioso J. Laboratory Biorisk
Management, 2015, CRC Press
2. FAO. Biosafety Resource Book Module A: SIR4003 SCIENCE COMMUNICATION
Introduction to Molecular Biology and Genetic
Engineering, 2011. This module will cover how science is communicated to the
3. Chau D.M. et al. (2018). Malaysian Educational public and in different media, with regards to science-
Module on Responsible Conduct of Research, related issues in society. Topics on the roles and
2018, Akademi Sains Malaysia . responsibilities of scientists in communicating scientific
research and science-related issues and the public
understanding of science; and how science is
SIR3019 HUMAN MOLECULAR GENETICS communicated on media will be covered. This module aims
to develop students’ communication and teamwork skills by
This course starts by looking at the content and showcasing their skills in science communication through
organization of the human genome. It involves describing various activities.
the gene related sequences (genes, introns, exons,
regulatory regions, pseudogenes etc.)and non-gene related Assessment Methods:
sequences. The student is then introduced to the Human Continuous Assessment: 100%
Genome Project and the processes involved. It includes
physical and genetic mapping. The second part will focus Main References:
on the methods of medical genetic research, with old and
new techniques. This includes functional cloning, positional 1. Bowater L. & Yeoman K. Science communication;
cloning and candidate gene approaches. At the end of the A practical guide for scientists, 1st ed, 2013, Wiley
course, students will be familiarised with current issues and

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